Browsing Brage NIH by Author "Raastad, Truls"
Now showing items 41-60 of 72
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Immunohistochemical changes in the expression of HSP27 in exercised human vastus lateralis muscle
Folkesson, Mattias; Mackey, Abigail L.; Holm, Lars; Kjær, Michael; Paulsen, Gøran; Raastad, Truls; Henriksson, Jan; Kadi, Fawzi (Peer reviewed; Journal article, 2008-06-28)Aim: The role of HSP27 in the adaptive process of skeletal muscle to exercise, especially in humans, is not well understood. The objective of this study was to investigate immunohistochemical changes in HSP27 expression ... -
Impact of resistance exercise on ribosome biogenesis is acutely regulated by post‐exercise recovery strategies
Figueiredo, Vandré C.; Roberts, Llion A.; Markworth, James F.; Barnett, Matthew P. G.; Coombes, Jeff S.; Raastad, Truls; Peake, Jonathan M.; Cameron-Smith, David (Journal article; Peer reviewed, 2016-01-26)Muscle hypertrophy occurs following increased protein synthesis, which requires activation of the ribosomal complex. Additionally, increased translational capacity via elevated ribosomal RNA (rRNA) synthesis has also been ... -
In-season strength maintenance training increases well-trained cyclists’ performance
Rønnestad, Bent R.; Hansen, Ernst Albin; Raastad, Truls (Journal article; Peer reviewed, 2010-08-27)We investigated the effects of strength maintenance training on thigh muscle cross-sectional area (CSA), leg strength, determinants of cycling performance, and cycling performance. Well-trained cyclists completed either ... -
Irisin and FNDC5: effects of 12-week strength training, and relations to muscle phenotype and body mass composition in untrained women
Ellefsen, Stian; Vikmoen, Olav; Slettaløkken, Gunnar; Whist, Jon Elling; Nygård, Håvard; Hollan, Ivana; Rauk, Irene; Vegge, Geir; Strand, Tor A.; Raastad, Truls; Rønnestad, Bent (Journal article; Peer reviewed, 2014-06-07)Purpose: To investigate the effects of strength training on abundances of irisin-related biomarkers in skeletal muscle and blood of untrained young women, and their associations with body mass composition, muscle phenotype ... -
Ischemic strength training: a low-load alternative to heavy resistance exercise?
Wernbom, Mathias; Augustsson, Jesper; Raastad, Truls (Peer reviewed; Journal article, 2008-05-04)Strength training with low loads in combination with vascular occlusion has been proposed as an alternative to heavy resistance exercise in the rehabilitation setting, especially when high forces acting upon the musculo-skeletal ... -
Mechanical properties of the patellar tendon in elite volleyball players with and without patellar tendinopathy
Helland, Christian; Bojsen-Møller, Jens; Raastad, Truls; Seynnes, Olivier R.; Moltubakk, Marie M.; Jakobsen, Vidar; Bahr, Roald (Journal article; Peer reviewed, 2013)Background: Although differences in mechanical properties between symptomatic and healthy tendons have been observed for the Achilles tendon, the impact of tendinopathy on patellar tendon mechanics is not fully documented. ... -
MicroRNAs in muscle: characterizing the powerlifter phenotype
D'Souza, Randall F.; Bjørnsen, Thomas; Zeng, Nina; Aasen, Kirsten M. M.; Raastad, Truls; Cameron-Smith, David; Mitchell, Cameron J. (Journal article; Peer reviewed, 2017-06-07)Powerlifters are the epitome of muscular adaptation and are able to generate extreme forces. The molecular mechanisms underpinning the significant capacity for force generation and hypertrophy are not fully elucidated. ... -
Modulating exercise-induced hormesis: does less equal more?
Peake, Jonathan M.; Markworth, James F.; Nosaka, Kazunori; Raastad, Truls; Wadley, Glenn D.; Coffey, Vernon G. (Journal article; Peer reviewed, 2015-08-01)Hormesis encompasses the notion that low levels of stress stimulate or upregulate existing cellular and molecular pathways that improve the capacity of cells and organisms to withstand greater stress. This notion underlies ... -
Muscle protein breakdown is impaired during immobilization compared to during a subsequent retraining period in older men: no effect of anti-inflammatory medication
Dideriksen, K.; Reitelseder, Søren; Agergaard, J.; Boesen, A.P.; Aas, Sigve Nyvik; Raastad, Truls; Holm, Lars (Peer reviewed; Journal article, 2020)Muscle inactivity reduces muscle protein synthesis (MPS), whereas a subsequent period of rehabilitation resistance training (retraining) increases MPS. However, less is known regarding muscle protein breakdown (MPB) during ... -
Muscle strength is associated with physical function in community-dwelling older adults receiving home care: A cross-sectional study
Bårdstu, Hilde Bremseth; Andersen, Vidar; Fimland, Marius Steiro; Raastad, Truls; Sæterbakken, Atle Hole (Peer reviewed; Journal article, 2022)Background: Higher maximal- and explosive strength is associated with better physical function among older adults. Although the relationship between isometric maximal strength and physical function has been examined, few ... -
Muscular HSP70 content is higher in elderly compared to young, but is normalized after 12 weeks of strength training
Cumming, Kristoffer Toldnes; Kvamme, Nils Helge; Schaad, Laura; Ugelstad, Ingrid; Raastad, Truls (Peer reviewed; Journal article, 2021)Purpose: Aging is associated with increased myocellular stress and loss of muscle mass and function. Heat shock proteins (HSPs) are upregulated during periods of stress as part of the cells protective system. Exercise can ... -
Musculoskeletal adaptations to strength training in frail elderly: A matter of quantity or quality?
Aas, Sigve Nyvik; Breit, Markus; Karsrud, Stian; Aase, Ole Jølle; Rognlien, Simen Helset; Cumming, Kristoffer Toldnes; Reggiani, Carlo; Seynnes, Olivier R.; Rossi, Andrea; Toniolo, Luana; Raastad, Truls (Peer reviewed; Journal article, 2020)Background The improvement in muscle strength generally exceeds the increase in muscle size following strength training in frail elderly, highlighting the complex aetiology of strength deficit in aging. The aim of this ... -
Native whey induces similar post exercise muscle anabolic responses as regular whey, despite greater leucinemia, in elderly individuals
Hamarsland, Håvard; Aas, Sigve Nyvik; Nordengen, Anne Lene; Holte, Kari; Garthe, Ina; Paulsen, Gøran; Cotter, Matthew; Børsheim, Elisabet; Benestad, Haakon Breien; Raastad, Truls (Journal article; Peer reviewed, 2018)Objective: Elderly muscle seems less sensitive to the anabolic stimulus of a meal. Changes in blood concentrations of leucine are suggested as one important trigger of the anabolic response in muscle. The aim of this study ... -
Native whey protein with high levels of leucine results in similar post-exercise muscular anabolic responses as regular whey protein: A randomized controlled trial
Hamarsland, Håvard; Nordengen, Anne Lene; Aas, Sigve Nyvik; Holte, Kristin Tosterud; Garthe, Ina; Paulsen, Gøran; Cotter, Matthew; Børsheim, Elisabet; Benestad, Haakon Breien; Raastad, Truls (Academic article, 2017-11-21)Protein ingestion produces a strong anabolic stimulus that elevates muscle protein synthesis [34]. The ability of a serving of protein to stimulate muscle protein synthesis (MPS) is dependent on absorption and blood kinetics ... -
No Difference Between Spray Dried Milk and Native Whey Supplementation with Strength Training
Hamarsland, Håvard; Handegard, Vilde; Kåshagen, Mauritz; Benestad, Haakon Breien; Raastad, Truls (Journal article; Peer reviewed, 2018)Background: A rapid digestibility and high leucine content are considered important for maximal stimulation of muscle protein synthesis. Consequently, with these properties, native whey may hold greater anabolic potential ... -
The Phys-Can observational study: adjuvant chemotherapy is associated with a reduction whereas physical activity level before start of treatment is associated with maintenance of maximal oxygen uptake in patients with cancer
Wiestad, Tor Helge; Raastad, Truls; Nordin, Karin; Igelström, Helena; Henriksson, Anna; Demmelmaier, Ingrid; Berntsen, Sveinung (Peer reviewed; Journal article, 2020)Background: Adjuvant therapy may cause multiple sideeffects on long term health, including reduced cardiorespiratory fitness (CRF) in patients with breast cancer (1, 2). However, there is currently limited knowledge regarding ... -
Physiological elevation of endogenous hormones results in superior strength training adaptation
Rønnestad, Bent R.; Nygaard, Håvard; Raastad, Truls (Journal article; Peer reviewed, 2011)The purpose of this study was to determine the influence of transiently elevated endogenous hormone concentrations during exercise on strength training adaptations. Nine subjects performed four unilateral strength training ... -
Polyneuropathy in adolescent childhood cancer survivors: The PACCS study
Andries, Aristomo; Ørstavik, Kristin; Rueegg, Corina Silvia; Eng, Sindre; Edvardsen, Elisabeth; Torsvik, Ingrid Kristin; Raastad, Truls; Ruud, Ellen; Nilsen, Kristian Bernhard; Allen, Sara-Maria (Peer reviewed; Journal article, 2022)Background: Childhood cancer survivors (CCS) are at risk of polyneuropathy due to chemotherapy, but studies in young survivors are scarce and diagnosis is challenging. We aimed to study the presence of polyneuropathy and ... -
Post-exercise cold water immersion attenuates acute anabolic signalling and long-term adaptations in muscle to strength training
Roberts, Llion A.; Raastad, Truls; Markworth, James F.; Figueiredo, Vandre C.; Egner, Ingrid M.; Shield, Anthony; Cameron-Smith, David; Coombes, Jeff S.; Peake, Jonathan M. (Journal article; Peer reviewed, 2015-08-13)We investigated functional, morphological and molecular adaptations to strength training exercise and cold water immersion (CWI) through two separate studies. In one study, 21 physically active men strength trained for 12 ... -
Postmenopausal osteoporosis is a musculoskeletal disease with a common genetic trait which responds to strength training: a translational intervention study
Olstad, Ole Kristoffer; Gautvik, Vigdis Teig; LeBlanc, Marissa Erin; Kvernevik, Karl Johnny; Utheim, Tor Paaske; Runningen, Anne; Wiig, Håvard; Kirkegaard, Camilla; Raastad, Truls; Reppe, Sjur; Gautvik, Kaare M. (Peer reviewed; Journal article, 2020)Background: Clinical evidence suggests that body muscle mass is positively associated with bone mass, of significance for the elderly population at risk of osteoporosis (OP). Furthermore, muscle and bone interact mechanically ...