Browsing Brage NIH by Author "Wareham, Nicholas J."
Now showing items 1-10 of 10
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Association between objectively assessed sedentary time and physical activity with metabolic risk factors among people with recently diagnosed type 2 diabetes
Cooper, Andrew J. M.; Brage, Søren; Ekelund, Ulf; Wareham, Nicholas J.; Griffin, Simon J.; Simmons, Rebecca K. (Journal article; Peer reviewed, 2013-10-03)Aims/hypothesis: The aim of our study was to examine the associations between sedentary time (SED-time), time spent in moderate-to-vigorous-intensity physical activity (MVPA), total physical activity energy expenditure ... -
Cardiorespiratory fitness assessment using risk-stratified exercise testing and dose–response relationships with disease outcomes
Gonzales, Tomas I.; Westgate, Kate; Strain, Tessa; Hollidge, Stefanie; Jeon, Justin; Christensen, Dirk L.; Jensen, Jørgen; Wareham, Nicholas J.; Brage, Søren (Peer reviewed; Journal article, 2021)Cardiorespiratory fitness (CRF) is associated with mortality and cardiovascular disease, but assessing CRF in the population is challenging. Here we develop and validate a novel framework to estimate CRF (as maximal oxygen ... -
Comparison of the EPIC physical activity questionnaire with combined heart rate and movement sensing in a nationally representative sample of older British adults
España-Romero, Vanesa; Golubic, Rajna; Martin, Kathryn R.; Hardy, Rebecca; Ekelund, Ulf; Kuh, Diana; Wareham, Nicholas J.; Cooper, Rachel; Brage, Søren (Journal article; Peer reviewed, 2014-02-06)Objectives: To compare physical activity (PA) subcomponents from EPIC Physical Activity Questionnaire (EPAQ2) and combined heart rate and movement sensing in older adults. Methods: Participants aged 60–64y from the MRC ... -
Estimation of free-living energy expenditure by heart rate and movement sensing: a doubly-labelled water study.
Brage, Søren; Westgate, Kate; Franks, Paul W.; Stegle, Oliver; Wright, Antony; Ekelund, Ulf; Wareham, Nicholas J. (Journal article; Peer reviewed, 2015-09-08)Background: Accurate assessment of energy expenditure (EE) is important for the study of energy balance and metabolic disorders. Combined heart rate (HR) and acceleration (ACC) sensing may increase precision of physical ... -
Examining the causal association of fasting glucose with blood pressure in healthy children and adolescents: a Mendelian randomization study employing common genetic variants of fasting glucose
Goharian, T. S.; Andersen, Lars Bo; Franks, Paul W,; Wareham, Nicholas J.; Brage, Søren; Veidebaum, T.; Ekelund, Ulf; Lawlor, Debbie A.; Loos, Ruth J. F.; Grøntved, Anders (Journal article; Peer reviewed, 2014-07-31)The aim of the study was to determine whether genetically raised fasting glucose (FG) levels are associated with blood pressure (BP) in healthy children and adolescents. We used 11 common genetic variants of FG discovered ... -
Heritability of objectively assessed daily physical activity and sedentary behavior
den Hoed, Marcel; Brage, Søren; Zhao, Jing Hua; Westgate, Kate; Nessa, Ayrun; Ekelund, Ulf; Spector, Tim D.; Wareham, Nicholas J.; Loos, Ruth J. F. (Journal article; Peer reviewed, 2013-09-18)Background: Twin and family studies that estimated the heritability of daily physical activity have been limited by poor measurement quality and a small sample size. Objective: We examined the heritability of daily ... -
Levels of physical activity among a nationally representative sample of people in early old age: results of objective and self-reported assessments
Golubic, Rajna; Martin, Kathryn R.; Ekelund, Ulf; Hardy, Rebecca; Wareham, Nicholas J.; Cooper, Rachel; Brage, Søren (Journal article; Peer reviewed, 2014-05-03)Detailed assessment of physical activity (PA) in older adults is required to comprehensively describe habitual PA-levels in this growing population segment. Current evidence of population PA-levels is predominantly based ... -
Multiple behaviour change intervention and outcomes in recently diagnosed type 2 diabetes: the ADDITION-Plus randomised controlled trial
Griffin, Simon J.; Simmons, Rebecca K.; Prevost, A. Toby; Williams, Kate M.; Hardeman, Wendy; Sutton, Stephen; Brage, Søren; Ekelund, Ulf; Parker, Richard A.; Wareham, Nicholas J.; Kinmonth, Ann Louise (Journal article; Peer reviewed, 2014-04-24)The aim of this study was to assess whether or not a theory-based behaviour change intervention delivered by trained and quality-assured lifestyle facilitators can achieve and maintain improvements in physical activity, ... -
Physical activity and all-cause mortality across levels of overall and abdominal adiposity in European men and women: the European prospective investigation into cancer and nutrition study (EPIC)
Ekelund, Ulf; Ward, Heather A.; Norat, Teresa; Luan, Jian'an; May, Anne M.; Weiderpass, Elisabete; Sharp, Stephen J.; Overvad, Kim; Østergaard, Jane Nautrup; Tjønneland, Anne; Johnsen, Nina Føns; Mesrine, Sylvie; Fournier, Agnès; Fagherazzi, Guy; Trichopoulou, Antonia; Lagiou, Pagona; Trichopoulos, Dimitrios; Li, Kuanrong; Kaaks, Rudolf; Ferrari, Pietro; Licaj, Idlir; Jenab, Mazda; Bergmann, Manuela; Boeing, Heiner; Palli, Domenico; Sieri, Sabina; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Peeters, Petra H.; Monnikhof, Evelyn; Bueno-de-Mesquita, H. Bas; Quirós, José Ramón; Agudo, Antonio; Sánchez, María-José; Huerta, José-Maria; Ardanaz, Eva; Arriola, Larraitz; Hedblad, Bo; Wirfält, Elisabet; Sund, Malin; Johansson, Mattias; Key, Timothy J.; Travis, Ruth C.; Khaw, Kay-Tee; Brage, Søren; Wareham, Nicholas J.; Riboli, Elio (Journal article; Peer reviewed, 2015-01-14)Background: The higher risk of death resulting from excess adiposity may be attenuated by physical activity (PA). However, the theoretical number of deaths reduced by eliminating physical inactivity compared with overall ... -
Physical activity, sedentary time and gain in overall and central body fat: 7-year follow-up of the ProActive trial cohort
Golubic, Rajna; Wijndaele, Katrien; Sharp, Stephen J.; Griffin, Simon J.; Wareham, Nicholas J.; Ekelund, Ulf; Brage, Søren (Journal article; Peer reviewed, 2014-05-20)Objective: The objective of this study is to examine the independent associations of time spent in moderate-to-vigorous physical activity (MVPA) and sedentary (SED-time), with total and abdominal body fat (BF), and the ...