• Human skeletal muscle fibre contractile properties and proteomic profile: adaptations to 3 weeks of unilateral lower limb suspension and active recovery 

      Brocca, Lorenza; Longa, Emanuela; Cannavino, Jessica; Seynnes, Olivier R.; de Vito, Giuseppe; McPhee, Jamie; Narici, Marco; Pellegrino, Maria Antonietta; Bottinelli, Roberto (Journal article; Peer reviewed, 2015-12-15)
      Following disuse, muscle fibre function goes through adaptations such as a loss of specific force (PO/CSA) and an increase in unloaded shortening velocity, which could be a result of both quantitative changes (i.e. atrophy) ...
    • Sarcolab pilot study into skeletal muscle’s adaptation to long-term spaceflight 

      Rittweger, Jörn; Albracht, Kirsten; Flück, Martin; Ruoss, Severin; Brocca, Lorenza; Longa, Emanuela; Moriggi, Manuela; Seynnes, Olivier R.; di Giulio, Irene; Tenori, Leonardo; Vignoli, Alessia; Capri, Miriam; Gelfi, Cecilia; Luchinat, Claudio; Franceschi, Claudio; Bottinelli, Roberto; Cerretelli, Paolo; Narici, Marco (Journal article; Peer reviewed, 2018)
      Spaceflight causes muscle wasting. The Sarcolab pilot study investigated two astronauts with regards to plantar flexor muscle size, architecture, and function, and to the underlying molecular adaptations in order to further ...
    • Structure and function of human muscle fibres and muscle proteome in physically active older men 

      Brocca, Lorenza; McPhee, Jamie; Longa, Emanuela; Canepari, Monica; Seynnes, Olivier R.; de Vito, Giuseppe; Pellegrino, Maria A.; Narici, Marco; Bottinelli, Roberto (Journal article; Peer reviewed, 2017)
      Contradictory results have been reported on the impact of ageing on structure and functions of skeletal muscle fibres, likely to be due to a complex interplay between ageing and other phenomena such as disuse and diseases. ...