• Effects and tolerability of exercise therapy modality on cardiorespiratory fitness in lung cancer: A randomized controlled trial 

      Scott, Jessica M.; Thomas, Samantha M.; Douglas, Pamela S.; Yu, Anthony F.; Rusch, Valerie; Huang, James; Capaci, Catherine; Harrison, Jenna N.; Stoeckel, Kurtis J.; Nilsen, Tormod Skogstad; Edvardsen, Elisabeth; Michalski, Meghan G.; Eves, Neil D.; Jones, Lee W.; Herndon II, James E. (Peer reviewed; Journal article, 2021)
      Background: Poor cardiorespiratory fitness (CRF) is a cardinal feature of post-treatment primary lung cancer. The most effective exercise therapy regimen to improve CRF has not been determined. Methods: In this ...
    • An epigenetic clock for human skeletal muscle 

      Voisin, Sarah; Harvey, Nicholas R; Haupt, Larisa M; Griffiths, Lyn R; Aston, Kevin J; Coffey, Vernon G.; Doering, Thomas M; Thompson, Jamie-Lee M; Benedict, Christian; Cedernaes, Jonathan; Lindholm, Malene E; Craig, Jeffrey M; Rowlands, David S; Sharples, Adam; Horvath, Steve; Eynon, Nir (Peer reviewed; Journal article, 2020)
      Background: Ageing is associated with DNA methylation changes in all human tissues, and epigenetic markers can estimate chronological age based on DNA methylation patterns across tissues. However, the construction of the ...
    • Meta-analysis of genome-wide DNA methylation and integrative omics of age in human skeletal muscle 

      Voisin, Sarah; Jacques, Macsue; Landen, Shanie; Harvey, Nicholas R.; Haupt, Larisa M.; Griffiths, Lyn R.; Gancheva, Sofiya; Ouni, Meriem; Jähnert, Marcus; Ashton, Kevin J.; Coffey, Vernon G.; Thompson, Jamie-Lee M.; Doering, Thomas M.; Gabory, Anne; Junien, Claudine; Caiazzo, Robert; Verkindt, Hélène; Raverdy, Violetta; Pattou, Francois; Froguel, Philippe; Blocquiaux, Sara; Thomis, Martine; Roden, Michael; Horvath, Steve; Eynon, Nir; Craig, Jeffrey M.; Sharples, Adam P.; Schürmann, Annette (Peer reviewed; Journal article, 2021)
      Background Knowledge of age-related DNA methylation changes in skeletal muscle is limited, yet this tissue is severely affected by ageing in humans. Methods We conducted a large-scale epigenome-wide association ...
    • Musculoskeletal adaptations to strength training in frail elderly: A matter of quantity or quality? 

      Aas, Sigve Nyvik; Breit, Markus; Karsrud, Stian; Aase, Ole Jølle; Rognlien, Simen Helset; Cumming, Kristoffer Toldnes; Reggiani, Carlo; Seynnes, Olivier R.; Rossi, Andrea; Toniolo, Luana; Raastad, Truls (Peer reviewed; Journal article, 2020)
      Background The improvement in muscle strength generally exceeds the increase in muscle size following strength training in frail elderly, highlighting the complex aetiology of strength deficit in aging. The aim of this ...
    • Stair climbing and mortality: A prospective cohort study from the UK Biobank 

      Sanchez-Lastra, Miguel A.; Ding, Ding; Dalene, Knut Eirik; Ekelund, Ulf; Tarp, Jakob; del Pozo Cruz, Borja (Peer reviewed; Journal article, 2021)
      Background Regular stair climbing has the potential to lower the risk of premature death, but current evidence is scarce. We aimed to examine whether daily stair climbing is associated with lower risk of all-cause, ...