• A randomised controlled study of the long-term effects of exercise training on mortality in elderly people: study protocol for the Generation 100 study 

      Stensvold, Dorthe; Viken, Hallgeir; Rognmo, Øyvind; Skogvoll, Eirik; Steinshamn, Sigurd Loe; Vatten, Lars Johan; Coombes, Jeff S.; Anderssen, Sigmund A.; Magnussen, Jon; Ingebrigtsen, Jan Erik; Singh, Maria A. Fiatarone; Langhammer, Arnulf; Støylen, Asbjørn; Helbostad, Jorunn L.; Wisløff, Ulrik (Journal article; Peer reviewed, 2015)
      Introduction: Epidemiological studies suggest that exercise has a tremendous preventative effect on morbidity and premature death, but these findings need to be confirmed by randomised trials. Generation 100 is a ...
    • Effect of exercise training for five years on all cause mortality in older adults-The Generation 100 study: Randomised controlled trial 

      Stensvold, Dorthe; Viken, Hallgeir; Steinshamn, Sigurd Loe; Dalen, Håvard; Støylen, Asbjørn; Loennechen, Jan Pål; Reitlo, Line Skarsem; Zisko, Nina; Bækkerud, Fredrik Hjulstad; Tari, Atefe R; Bucher Sandbakk, Silvana; Carlsen, Trude; Ingebrigtsen, Jan Erik; Lydersen, Stian; Mattsson, Erney; Anderssen, Sigmund Alfred; Singh, Maria A. Fiatarone; Coombes, Jeff S.; Skogvoll, Eirik; Vatten, Lars Johan; Helbostad, Jorunn L.; Rognmo, Øivind; Wisløff, Ulrik (Peer reviewed; Journal article, 2020)
      Objective: To evaluate the effect of five years of supervised exercise training compared with recommendations for physical activity on mortality in older adults (70-77 years). Design: Randomised controlled trial. Setting: ...
    • Human skeletal muscle plasmalemma alters its structure to change its Ca2+-handling following heavy-load resistance exercise 

      Cully, Tanya R.; Murphy, Robyn M.; Roberts, Llion A.; Raastad, Truls; Fassett, Robert G.; Coombes, Jeff S.; Jayasinghe, Isuru D.; Launikonis, Bradley S. (Journal article; Peer reviewed, 2017)
      High-force eccentric exercise results in sustained increases in cytoplasmic Ca2+ levels ([Ca2+]cyto), which can cause damage to the muscle. Here we report that a heavy-load strength training bout greatly alters the structure ...
    • Impact of resistance exercise on ribosome biogenesis is acutely regulated by post‐exercise recovery strategies 

      Figueiredo, Vandré C.; Roberts, Llion A.; Markworth, James F.; Barnett, Matthew P. G.; Coombes, Jeff S.; Raastad, Truls; Peake, Jonathan M.; Cameron-Smith, David (Journal article; Peer reviewed, 2016-01-26)
      Muscle hypertrophy occurs following increased protein synthesis, which requires activation of the ribosomal complex. Additionally, increased translational capacity via elevated ribosomal RNA (rRNA) synthesis has also been ...
    • Post-exercise cold water immersion attenuates acute anabolic signalling and long-term adaptations in muscle to strength training 

      Roberts, Llion A.; Raastad, Truls; Markworth, James F.; Figueiredo, Vandre C.; Egner, Ingrid M.; Shield, Anthony; Cameron-Smith, David; Coombes, Jeff S.; Peake, Jonathan M. (Journal article; Peer reviewed, 2015-08-13)
      We investigated functional, morphological and molecular adaptations to strength training exercise and cold water immersion (CWI) through two separate studies. In one study, 21 physically active men strength trained for 12 ...