Browsing Brage NIH by Author "Erskine, Robert M."

Now showing items 1-2 of 2

    • Costamere remodeling with muscle loading and unloading in healthy young men 

      Li, Ruowei; Narici, Marco V.; Erskine, Robert M.; Seynnes, Olivier R.; Rittweger, Jörn; Pisot, Rado; Simunic, Bostjan; Flück, Martin (Journal article; Peer reviewed, 2013-09-08)
      Costameres are mechano-sensory sites of focal adhesion in the sarcolemma that provide a structural anchor for myofibrils. Their turnover is regulated by integrin-associated focal adhesion kinase (FAK). We hypothesized that ...

    • DNA methylation across the genome in aged human skeletal muscle tissue and muscle‑derived cells: The role of HOX genes and physical activity 

      Turner, Daniel C.; Gorski, Piotr Patryk; Massar, Mohd Firdaus; Seaborne, Robert A.; Baumert, Phillipp; Brown, Alexander D.; Erskine, Robert M.; Dos-Remedios, Ian; Voisin, Sarah; Eynon, Nir; Borisov, Oleg; Larin, Andrey; Semenova, Ekaterina A.; Popov, Daniil; Drust, Barry; Owens, Daniel J.; Ahmetov, Ildus I.; Sharples, Adam; Kitchen, Mark O.; Sultanov, R. I.; Generozov, Edward V.; Stewart, Claire E. (Peer reviewed; Journal article, 2020)
      Skeletal muscle tissue demonstrates global hypermethylation with age. However, methylome changes across the time-course of differentiation in aged human muscle derived cells, and larger coverage arrays in aged muscle tissue ...