Browsing Brage NIH by Author "Holen, Torgeir"

Now showing items 1-7 of 7

    • Dual specificity phosphatase 5 and 6 are oppositely regulated in human skeletal muscle by acute exercise 

      Pourteymour, Shirin; Hjorth, Marit; Lee-Ødegård, Sindre; Holen, Torgeir; Langleite, Torgrim Mikal; Jensen, Jørgen; Birkeland, Kåre I.; Drevon, Christian A; Eckardt, Kristin (Journal article; Peer reviewed, 2017)
      Physical activity promotes specific adaptations in most tissues including skeletal muscle. Acute exercise activates numerous signaling cascades including pathways involving mitogen‐activated protein kinases (MAPKs) such ...

    • Effect of energy restriction and physical exercise intervention on phenotypic flexibility as examined by transcriptomics analyses of mRNA from adipose tissue and whole body magnetic resonance imaging 

      Lee, Sindre; Norheim, Frode; Langleite, Torgrim M.; Noreng, Hans J.; Storås, Trygve H.; Afman, Lydia A.; Frost, Gary; Bell, Jimmy D.; Thomas, E. Louise; Kolnes, Kristoffer J.; Tangen, Daniel S.; Stadheim, Hans Kristian; Gilfillan, Gregor D.; Gulseth, Hanne L.; Birkeland, Kåre I.; Jensen, Jørgen; Drevon, Christian A.; Holen, Torgeir (Journal article; Peer reviewed, 2016-11-07)
      Overweight and obesity lead to changes in adipose tissue such as inflammation and reduced insulin sensitivity. The aim of this study was to assess how altered energy balance by reduced food intake or enhanced physical ...

    • Global mRNA sequencing of human skeletal muscle: Search for novel exercise-regulated myokines 

      Pourteymour, Shirin; Eckardt, Kristin; Holen, Torgeir; Langleite, Torgrim Mikal; Lee, Sindre; Jensen, Jørgen; Birkeland, Kåre I.; Drevon, Christian A.; Hjorth, Marit (Journal article; Peer reviewed, 2017-01)
      Objective: Skeletal muscle is an important secretory organ, producing and releasing numerous myokines, which may be involved in mediating beneficial health effects of physical activity. More than 100 myokines have been ...

    • Interaction between plasma fetuin‐A and free fatty acids predicts changes in insulin sensitivity in response to long‐term exercise 

      Lee, Sindre; Norheim, Frode; Gulseth, Hanne L.; Langleite, Torgrim M.; Kolnes, Kristoffer J.; Tangen, Daniel S.; Stadheim, Hans Kristian; Gilfillan, Gregor D.; Holen, Torgeir; Birkeland, Kåre I,; Jensen, Jørgen; Drevon, Christian A. (Journal article; Peer reviewed, 2017-03)
      The hepatokine fetuin‐A can together with free fatty acids (FFAs) enhance adipose tissue (AT) inflammation and insulin resistance via toll‐like receptor 4 (TLR4). Although some of the health benefits of exercise can be ...

    • Regulation of angiopoietin-like protein 4 Production during and after exercise 

      Norheim, Frode; Hjorth, Marit; Langleite, Torgrim Mikal; Lee, Sindre; Holen, Torgeir; Bindesbøll, Christian; Stadheim, Hans Kristian; Gulseth, Hanne Lovdal; Birkeland, Kåre I.; Kielland, Anders; Jensen, Jørgen; Dalen, Knut Tomas; Drevon, Christian A. (Journal article; Peer reviewed, 2014-08-19)
      Angiopoietin-like protein 4 (ANGPTL4) may regulate lipoprotein lipase-dependent plasma clearance of triacylglycerol from skeletal muscle during exercise. The aim of this study was to examine the importance of muscle in ...

    • Subsarcolemmal lipid droplet responses to a combined endurance and strength exercise intervention 

      Li, Yuchuan; Lee, Sindre; Langleite, Torgrim; Norheim, Frode; Pourteymour, Shirin; Jensen, Jørgen; Stadheim, Hans Kristian; Storås, Tryggve H.; Davanger, Svend; Gulseth, Hanne L.; Birkeland, Kåre I.; Drevon, Christian A.; Holen, Torgeir (Journal article; Peer reviewed, 2014)
      Muscle lipid stores and insulin sensitivity have a recognized association although the mechanism remains unclear. We investigated how a 12‐week supervised combined endurance and strength exercise intervention influenced ...

    • The effect of acute and long‐term physical activity on extracellular matrix and serglycin in human skeletal muscle 

      Hjorth, Marit; Norheim, Frode; Meen, Astri Jeanette; Pourteymour, Shirin; Lee, Sindre; Holen, Torgeir; Jensen, Jørgen; Birkeland, Kåre I.; Martinov, Vladimir Nikolkaev; Langleite, Torgrim Mikal; Eckardt, Kristin; Drevon, Christian A.; Kolset, Svein Olav (Journal article; Peer reviewed, 2015-08-19)
      Remodeling of extracellular matrix (ECM), including regulation of proteoglycans in skeletal muscle can be important for physiological adaptation to exercise. To investigate the effects of acute and long‐term exercise on ...