• Antioxidant enzymes and Nrf2/Keap1 in human skeletal muscle: Influence of age, sex, adiposity and aerobic fitness 

      Galvan-Alvarez, Victor; Gallego-Selles, Angel; Martinez-Canton, Miriam; García-Gonzalez, Eduardo; Gelabert-Rebato, Miriam; Ponce-Gonzalez, Jesus Gustavo; Larsen, Steen; Morales-Alamo, David; Losa-Reyna, Jose; Perez-Suarez, Ismael; Dorado, Cecilia; Perez-Valera, Mario; Holmberg, Hans-Christer; Boushel, Robert; Velasco, Pedro de Pablos; Helge, Jørn Wulff; Martin-Rincon, Marcos; Calbet, José Antonio López (Peer reviewed; Journal article, 2023)
      Ageing, a sedentary lifestyle, and obesity are associated with increased oxidative stress, while regular exercise is associated with an increased antioxidant capacity in trained skeletal muscles. Whether a higher aerobic ...
    • Determinants of the maximal functional reserve during repeated supramaximal exercise by humans: The roles of Nrf2/Keap1, antioxidant proteins, muscle phenotype and oxygenation 

      Galvan-Alvarez, Victor; Martin-Rincon, Marcos; Gallego-Selles, Angel; Martínez Canton, Miriam; HamedChaman, NaDer; Gelabert-Rebato, Miriam; Perez-Valera, Mario; García-Gonzalez, Eduardo; Santana, Alfredo; Holmberg, Hans-Christer; Boushel, Robert; Hallén, Jostein; Calbet, Jose Antonio Lopez (Peer reviewed; Journal article, 2023)
      When high-intensity exercise is performed until exhaustion a “functional reserve” (FR) or capacity to produce power at the same level or higher than reached at exhaustion exists at task failure, which could be related to ...
    • Effects of training, detraining, and retraining on strength, hypertrophy, and myonuclear number in human skeletal muscle 

      Psilander, Niklas; Eftestøl, Einar; Cumming, Kristoffer Toldnes; Solgård, Inga Juvkam; Ekblom, Maria M.; Sunding, Kerstin; Wernbom, Mathias; Holmberg, Hans-Christer; Ekblom, Björn; Bruusgaard, Jo C.; Raastad, Truls; Gundersen, Kristian (Peer reviewed; Journal article, 2019)
      Previously trained mouse muscles acquire strength and volume faster than naïve muscles; it has been suggested that this is related to increased myonuclear density. The present study aimed to determine whether a previously ...
    • Exercise mitigates the loss of muscle mass by attenuating the activation of autophagy during severe energy deficit 

      Martin-Rincon, Marcos; Pérez-López, Antonio; Morales-Alamo, David; Perez-Suarez, Ismael; de Pablos-Velasco, Pedro; Perez-Valera, Mario; Perez-Regalado, Sergio; Martinez-Canton, Miriam; Gelabert-Rebato, Miriam; Juan-Habib, Julian William; Holmberg, Hans-Christer; Calbet, Jose Antonio Lopez (Peer reviewed; Journal article, 2019)
      The loss of skeletal muscle mass with energy deficit is thought to be due to protein breakdown by the autophagy-lysosome and the ubiquitin-proteasome systems. We studied the main signaling pathways through which exercise ...
    • Mitochondrial oxygen affinity increases after sprint interval training and is related to the improvement in peak oxygen uptake 

      Larsen, Filip J.; Schiffer, Tomas A.; Zinner, Christoph; Willis, Sarah J.; Morales-Alamo, David; Calbet, Jose Antonio Lopez; Boushel, Robert; Holmberg, Hans-Christer (Peer reviewed; Journal article, 2020)
      Aims: The body responds to exercise training by profound adaptations throughout the cardiorespiratory and muscular systems, which may result in improvements in maximal oxygen consumption (VO2peak) and mitochondrial capacity. ...
    • The physiological capacity of the world's highest ranked female cross-country skiers 

      Sandbakk, Øyvind; Hegge, Ann Magdalen; Losnegard, Thomas; Skattebo, Øyvind; Tønnessen, Espen; Holmberg, Hans-Christer (Journal article; Peer reviewed, 2016-06)
      Purpose: The objective of this study is to compare the physiological capacity and training characteristics of the world_s six highest ranked female cross-country skiers (world class (WC)) with those of six competitors of ...
    • The Training of Olympic Alpine Ski Racers 

      Gilgien, Matthias; Reid, Robert Cortas; Raschner, Christian; Supej, Matej; Holmberg, Hans-Christer (Journal article; Peer reviewed, 2018)
      Alpine combined was the only alpine ski racing event at the first Winter Olympic Games in 1936, but since then, slalom, giant slalom, super-G, downhill, and team events have also become Olympic events. Substantial improvements ...