Browsing Brage NIH by Author "Lai, Yu-Chiang"
Now showing items 1-3 of 3
-
Beta-Adrenoceptor stimulation potentiates insulin-stimulated PKB phosphorylation in rat cardiomyocytes via cAMP and PKA
Stuenæs, Jorid T.; Bolling, Astrid; Ingvaldsen, Ada; Rommundstad, Camilla; Sudar, Emina; Lin, Fang-Chin; Lai, Yu-Chiang; Jensen, Jørgen (Journal article; Peer reviewed, 2010-03-23)BACKGROUND AND PURPOSE: Genetic approaches have documented protein kinase B (PKB) as a pivotal regulator of heart function. Insulin strongly activates PKB, whereas adrenaline is not considered a major physiological regulator ... -
Role of glycogen content on glucose uptake and glycogen synthase in skeletal muscles: The effect of contraction and insulin
Lai, Yu-Chiang (Doctoral thesis, 2010-04)The present thesis is based on 4 papers which have investigated contraction- and insulin-mediated regulations of glucose uptake and GS activation in skeletal muscles with different glycogen contents. The level of glycogen ... -
The role of skeletal muscle glycogen breakdown for regulation of insulin sensitivity by exercise
Jensen, Jørgen; Rustad, Per Inge; Kolnes, Anders Jensen; Lai, Yu-Chiang (Journal article; Peer reviewed, 2011-12-30)Glycogen is the storage form of carbohydrates in mammals. In humans the majority of glycogen is stored in skeletal muscles (∼500 g) and the liver (∼100 g). Food is supplied in larger meals, but the blood glucose concentration ...