• Angiotensin-converting enzyme 2 (SARS-CoV-2 receptor) expression in human skeletal muscle 

      Perez-Valera, Mario; Martinez-Canton, Miriam; Gallego-Selles, Angel; Gelabert-Rebato, Miriam; Morales-Alamo, David; Santana, Alfredo; Martin-Rodriguez, Saul; Larsen, Steen; Losa-Reyna, Jose; Perez-Suarez, Ismael; Dorado, Cecilia; Curtelin, David; Gonzalez-Henriquez, Juan Jose; Boushel, Robert; Hallén, Jostein; de Pablos-Velasco, Pedro; Freixinet-Gilart, Jorge; Calbet, Jose Antonio Lopez; Galván-Alvarez, Victor; Ponce-Gonzalez, Jesus Gustavo (Peer reviewed; Journal article, 2021)
      The study aimed to determine the levels of skeletal muscle angiotensin-converting enzyme 2 (ACE2, the SARS-CoV-2 receptor) protein expression in men and women and assess whether ACE2 expression in skeletal muscle is ...
    • Exercise mitigates the loss of muscle mass by attenuating the activation of autophagy during severe energy deficit 

      Martin-Rincon, Marcos; Pérez-López, Antonio; Morales-Alamo, David; Perez-Suarez, Ismael; de Pablos-Velasco, Pedro; Perez-Valera, Mario; Perez-Regalado, Sergio; Martinez-Canton, Miriam; Gelabert-Rebato, Miriam; Juan-Habib, Julian William; Holmberg, Hans-Christer; Calbet, Jose Antonio Lopez (Peer reviewed; Journal article, 2019)
      The loss of skeletal muscle mass with energy deficit is thought to be due to protein breakdown by the autophagy-lysosome and the ubiquitin-proteasome systems. We studied the main signaling pathways through which exercise ...
    • Regulation of Nrf2/Keap1 signalling in human skeletal muscle during exercise to exhaustion in normoxia, severe acute hypoxia and post-exercise ischaemia: Influence of metabolite accumulation and oxygenation 

      Gallego-Selles, Angel; Martin-Rincon, Marcos; Martinez-Canton, Miriam; Perez-Valera, Mario; Martín-Rodríguez, Saúl; Gelabert-Rebato, Miriam; Santana, Alfredo; Morales-Alamo, David; Dorado, Cecilia; Calbet, Jose Antonio Lopez (Peer reviewed; Journal article, 2020)
      The Nrf2 transcription factor is induced by reactive oxygen and nitrogen species and is necessary for the adaptive response to exercise in mice. It remains unknown whether Nrf2 signalling is activated by exercise in human ...
    • Supplementation with a mango leaf extract (Zynamite®) in combination with quercetin attenuates muscle damage and pain and accelerates recovery after strenuous damaging exercise 

      Martin-Rincon, Marcos; Gelabert-Rebato, Miriam; Galvan-Alvarez, Victor; Gallego-Selles, Angel; Martinez-Canton, Miriam; Lopez-Rios, Laura; Wiebe, Julia C.; Martin-Rodriguez, Saul; Arteaga-Ortiz, Rafael; Dorado, Cecilia; Perez-Regalado, Sergio; Santana, Alfredo; Morales-Alamo, David; Calbet, Jose Antonio Lopez (Peer reviewed; Journal article, 2020)
      Prolonged or unusual exercise may cause exercise-induced muscle damage (EIMD). To test whether Zynamite®, a mango leaf extract rich in the natural polyphenol mangiferin, administered in combination with quercetin facilitates ...