Blar i Brage NIH på forfatter "Martinez-Canton, Miriam"
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Angiotensin-converting enzyme 2 (SARS-CoV-2 receptor) expression in human skeletal muscle
Perez-Valera, Mario; Martinez-Canton, Miriam; Gallego-Selles, Angel; Gelabert-Rebato, Miriam; Morales-Alamo, David; Santana, Alfredo; Martin-Rodriguez, Saul; Larsen, Steen; Losa-Reyna, Jose; Perez-Suarez, Ismael; Dorado, Cecilia; Curtelin, David; Gonzalez-Henriquez, Juan Jose; Boushel, Robert; Hallén, Jostein; de Pablos-Velasco, Pedro; Freixinet-Gilart, Jorge; Calbet, Jose Antonio Lopez; Galván-Alvarez, Victor; Ponce-Gonzalez, Jesus Gustavo (Peer reviewed; Journal article, 2021)The study aimed to determine the levels of skeletal muscle angiotensin-converting enzyme 2 (ACE2, the SARS-CoV-2 receptor) protein expression in men and women and assess whether ACE2 expression in skeletal muscle is ... -
Antioxidant enzymes and Nrf2/Keap1 in human skeletal muscle: Influence of age, sex, adiposity and aerobic fitness
Galvan-Alvarez, Victor; Gallego-Selles, Angel; Martinez-Canton, Miriam; García-Gonzalez, Eduardo; Gelabert-Rebato, Miriam; Ponce-Gonzalez, Jesus Gustavo; Larsen, Steen; Morales-Alamo, David; Losa-Reyna, Jose; Perez-Suarez, Ismael; Dorado, Cecilia; Perez-Valera, Mario; Holmberg, Hans-Christer; Boushel, Robert; Velasco, Pedro de Pablos; Helge, Jørn Wulff; Martin-Rincon, Marcos; Calbet, José Antonio López (Peer reviewed; Journal article, 2023)Ageing, a sedentary lifestyle, and obesity are associated with increased oxidative stress, while regular exercise is associated with an increased antioxidant capacity in trained skeletal muscles. Whether a higher aerobic ... -
Exercise mitigates the loss of muscle mass by attenuating the activation of autophagy during severe energy deficit
Martin-Rincon, Marcos; Pérez-López, Antonio; Morales-Alamo, David; Perez-Suarez, Ismael; de Pablos-Velasco, Pedro; Perez-Valera, Mario; Perez-Regalado, Sergio; Martinez-Canton, Miriam; Gelabert-Rebato, Miriam; Juan-Habib, Julian William; Holmberg, Hans-Christer; Calbet, Jose Antonio Lopez (Peer reviewed; Journal article, 2019)The loss of skeletal muscle mass with energy deficit is thought to be due to protein breakdown by the autophagy-lysosome and the ubiquitin-proteasome systems. We studied the main signaling pathways through which exercise ... -
Fast regulation of the NF-κB signalling pathway in human skeletal muscle revealed by high-intensity exercise and ischaemia at exhaustion: Role of oxygenation and metabolite accumulation
Gallego-Selles, Angel; Galvan-Alvarez, Victor; Martinez-Canton, Miriam; Garcia-Gonzalez, Eduardo; Morales-Alamo, David; Santana, Alfredo; Gonzalez-Henriquez, Juan Jose; Dorado, Cecilia; Calbet, Jose Antonio Lopez; Martin-Rincon, Marcos (Peer reviewed; Journal article, 2022)The NF-κB signalling pathway plays a critical role in inflammation, immunity, cell proliferation, apoptosis, and muscle metabolism. NF-κB is activated by extracellular signals and intracellular changes in Ca2+, Pi, H+, ... -
A mango leaf extract (Zynamite®) combined with Quercetin has exercise-mimetic properties in human skeletal muscle
Martinez-Canton, Miriam; Galvan-Alvarez, Victor; Garcia-Gonzalez, Eduardo; Gallego-Selles, Angel; Gelabert-Rebato, Miriam; Garcia-Perez, Giovanni; Santana, Alfredo; Lopez-Rios, Laura; Vega-Morales, Tanausu; Martin-Rincon, Marcos; Calbet, Jose Antonio Lopez (Peer reviewed; Journal article, 2023)Zynamite PX®, a mango leaf extract combined with quercetin, enhances exercise performance by unknown molecular mechanisms. Twenty-five volunteers were assigned to a control (17 males) or supplementation group (8 males, ... -
Regulation of Nrf2/Keap1 signalling in human skeletal muscle during exercise to exhaustion in normoxia, severe acute hypoxia and post-exercise ischaemia: Influence of metabolite accumulation and oxygenation
Gallego-Selles, Angel; Martin-Rincon, Marcos; Martinez-Canton, Miriam; Perez-Valera, Mario; Martín-Rodríguez, Saúl; Gelabert-Rebato, Miriam; Santana, Alfredo; Morales-Alamo, David; Dorado, Cecilia; Calbet, Jose Antonio Lopez (Peer reviewed; Journal article, 2020)The Nrf2 transcription factor is induced by reactive oxygen and nitrogen species and is necessary for the adaptive response to exercise in mice. It remains unknown whether Nrf2 signalling is activated by exercise in human ... -
Supplementation with a mango leaf extract (Zynamite®) in combination with quercetin attenuates muscle damage and pain and accelerates recovery after strenuous damaging exercise
Martin-Rincon, Marcos; Gelabert-Rebato, Miriam; Galvan-Alvarez, Victor; Gallego-Selles, Angel; Martinez-Canton, Miriam; Lopez-Rios, Laura; Wiebe, Julia C.; Martin-Rodriguez, Saul; Arteaga-Ortiz, Rafael; Dorado, Cecilia; Perez-Regalado, Sergio; Santana, Alfredo; Morales-Alamo, David; Calbet, Jose Antonio Lopez (Peer reviewed; Journal article, 2020)Prolonged or unusual exercise may cause exercise-induced muscle damage (EIMD). To test whether Zynamite®, a mango leaf extract rich in the natural polyphenol mangiferin, administered in combination with quercetin facilitates ...