• Achieving energy balance with a high‐fat meal does not enhance skeletal muscle adaptation and impairs glycaemic response in a sleep‐low training model 

      Areta, José; Iraki, Juma; Owens, Daniel J.; Joanisse, Sophie; Philp, Andrew; Morton, James P.; Hallén, Jostein (Peer reviewed; Journal article, 2020)
      Training with low carbohydrate availability (LCHO) has been shown to acutely enhance endurance training skeletal muscle response, but the concomitant energy deficit (ED) in LCHO interventions has represented a confounding ...
    • Daily energy expenditure through the human life course 

      Pontzer, Herman; Yamada, Yosuke; Sagayama, Hiroyuki; Ainslie, Philip N.; Andersen, Lene Frost; Anderson, Liam J.; Arab, Lenore; Baddou, Issaad; Bedu-Addo, Kweku; Blaak, Ellen E.; Blanc, Stéphane; Bonomi, Alberto; Bouten, Carlijn V.C.; Bovet, Pascal; Buchowski, Maciej S.; Butte, Nancy F.; Camps, Stefan G.J.A.; Close, Graeme L.; Cooper, Jamie A.; Cooper, Richard; Das, Sai Krupa; Dugas, Lara R.; Ekelund, Ulf; Entringer, Sonja; Forrester, Terrence; Fudge, Barry W.; Goris, Annelies; Gurven, Michael; Hambly, Catherine; El Hamdouchi, Asmaa; Hoos, Marjije B.; Hu, Sumei; Joonas, Noorjehan; Joosen, Annemiek M.; Katzmarzyk, Peter; Kempen, Kitty P.; Kimura, Misaka; Kraus, William E.; Kushner, Robert F.; Lambert, Estelle V.; Leonard, William R.; Lessan, Nader; Martin, Corby K.; Medin, Anine Christine; Meijer, Erwin P.; Morehen, James C.; Morton, James P.; Neuhouser, Marian L.; Nicklas, Theresa A.; Ojiambo, Robert M.; Pietiläinen, Kirsi H.; Pitsiladis, Yannis P.; Plange-Rhule, Jacob; Plasqui, Guy; Prentice, Ross L.; Rabinovich, Roberto A.; Racette, Susan B.; Raichlen, David A.; Ravussin, Eric; Reynolds, Rebecca M.; Roberts, Susan B.; Schuit, Albertine J.; Sjödin, Anders; Stice, Eric; Urlacher, Samuel S.; Valenti, Giulio; Van Etten, Ludo M.; Van Mil, Edgar A.; Wells, Jonathan C.K.; Wilson, George; Wood, Brian M.; Yanovski, Jack; Yoshida, Tsukasa; Zhang, Xueying; Murphy-Alford, Alexia J.; Loechl, Cornelia U.; Luke, Amy; Rood, Jennifer C.; Schoeller, Dale A.; Westerterp, Klaas R.; Wong, William W.; Speakman, John R. (Peer reviewed; Journal article, 2021)
      Total daily energy expenditure (“total expenditure”) reflects daily energy needs and is a critical variable in human health and physiology, but its trajectory over the life course is poorly studied. We analyzed a large, ...
    • Energy compensation and adiposity in humans 

      Careau, Vincent; Halsey, Lewis G.; Pontzer, Herman; Ainslie, Philip N.; Andersen, Lene F.; Anderson, Liam J.; Arab, Lenore; Baddou, Issad; Bedu-Addo, Kweku; Blaak, Ellen E.; Blanc, Stephane; Bonomi, Alberto G.; Buchowski, Maciej S.; Butte, Nancy F.; Close, Graeme L.; Cooper, Jamie A.; Das, Sai Krupa; Cooper, Richard; Dugas, Lara R.; Eaton, Simon D.; Ekelund, Ulf; Entringer, Sonja; Forrester, Terrence; Fudge, Barry W.; Goris, Annelies H.; Gurven, Michael; Hambly, Catherine; El Hamdouchi, Asmaa; Hoos, Marije B.; Hu, Sumei; Joonas, Noorjehan; Joosen, Annemiek M.; Katzmarzyk, Peter; Kempen, Kitty P.; Kimura, Misaka; Kraus, William E.; Kushner, Robert F.; Lambert, Estelle V.; Leonard, William R.; Lessan, Nader; Martin, Corby K.; Medin, Anine C.; Meijer, Erwin P.; Morehen, James C.; Morton, James P.; Neuhouser, Marian L.; Nicklas, Theresa A.; Ojiambo, Robert M.; Pietiläinen, Kirsi H.; Pitsiladis, Yannis P.; Plange-Rhule, Jacob; Plasqui, Guy; Prentice, Ross L.; Rabinovich, Roberto A.; Racette, Susan B.; Raichlen, David A.; Ravussin, Eric; Reilly, John J.; Reynolds, Rebecca M.; Roberts, Susan B.; Schuit, Albertine J.; Sjödin, Anders M.; Stice, Eric; Urlacher, Samuel S.; Valenti, Giulio; Wilson, George; Wood, Brian M.; Yanovski, Jack; Yoshida, Tsukasa; Zhang, Xueying; Murphy-Alford, Alexia J.; Loechl, Cornelia U.; Luke, Amy H.; Rood, Jennifer; Sagayama, Hiroyuki; Schoeller, Dale A.; Wong, William W.; Yamada, Yosuke; Speakman, John R.; Bouten, Carlijn V. C.; Camps, Stefan G. J. A.; van Etten, Ludo M.; van Mil, Edgar A.; Wells, Jonathan C. K. (Peer reviewed; Journal article, 2021)
      Understanding the impacts of activity on energy balance is crucial. Increasing levels of activity may bring diminishing returns in energy expenditure because of compensatory responses in non-activity energy expenditures.1, ...
    • Graded reductions in pre-exercise glycogen concentration do not augment exercise-induced nuclear AMPK and PGC-1α protein content in human muscle 

      Hearris, Mark A.; Owens, Daniel J.; Strauss, Juliette A.; Shepherd, Sam O.; Sharples, Adam; Morton, James P.; Louis, Julien (Peer reviewed; Journal article, 2020)
      We examined the effects of graded muscle glycogen on the subcellular location and protein content of AMP‐activated protein kinase (AMPK) and peroxisome proliferator‐activated receptor γ coactivator 1α (PGC‐1α) and mRNA ...
    • PGC-1α alternative promoter (Exon 1b) controls augmentation of total PGC-1α gene expression in response to cold water immersion and low glycogen availability 

      Allan, Robert; Morton, James P.; Close, Graeme L.; Drust, Barry; Gregson, Warren; Sharples, Adam (Peer reviewed; Journal article, 2020)
      This investigation sought to determine whether post-exercise cold water immersion and low glycogen availability, separately and in combination, would preferentially activate either the Exon 1a or Exon 1b Peroxisome ...
    • Physical activity and fat-free mass during growth and in later life 

      Westerterp, Klaas R.; Yamada, Yosuke; Sagayama, Hiroyuki; Ainslie, Philip N.; Andersen, Lene F.; Anderson, Liam J.; Arab, Lenore; Baddou, Issaad; Bedu-Addo, Kweku; Blaak, Ellen E.; Blanc, Stéphane; Bovet, Pascal; Buchowski, Maciej S.; Butte, Nancy F.; Close, Graeme L.; Cooper, Jamie A.; Das, Sai Krupa; Cooper, Richard; Dugas, Lara R.; Ekelund, Ulf; Entringer, Sonja; Forrester, Terrence; Fudge, Barry W.; Gurven, Michael; Hambly, Catherine; El Hamdouchi, Asmaa; Hoos, Marije B.; Hu, Sumei; Joonas, Noorjehan; Joosen, Annemiek M.; Katzmarzyk, Peter; Kempen, Kitty P.; Kimura, Misaka; Kraus, William E.; Kushner, Robert F.; Lambert, Estelle V.; Leonard, William R.; Lessan, Nader; Martin, Corby K.; Medin, Anine Christine; Meijer, Erwin P.; Morehen, James C.; Morton, James P.; Neuhouser, Marian L.; Nicklas, Theresa A.; Ojiambo, Robert M.; Pietiläinen, Kirsi H.; Pitsiladis, Yannis P.; Plange-Rhule, Jacob; Plasqui, Guy; Prentice, Ross L.; Rabinovich, Roberto A.; Racette, Susan B.; Raichlen, David A.; Ravussin, Eric; Reynolds, Rebecca M.; Roberts, Susan B.; Schuit, Albertine J.; Stice, Eric; Urlacher, Samuel S.; Valenti, Giulio; Wilson, George; Wood, Brian M.; Yanovski, Jack; Yoshida, Tsukasa; Zhang, Xueying; Murphy-Alford, Alexia J.; Loechl, Cornelia U.; Luke, Amy; Pontzer, Herman; Rood, Jennifer C.; Schoeller, Dale A.; Wong, William W.; Speakman, John R.; Bonomi, Alberto G.; Bouten, Carlijn V. C.; Camps, Stefan G. J. A.; Goris, Annelies H.; Sjödin, Anders M.; van Etten, Ludo M.; van Mil, Edgar A.; Wells, Jonathan C. K. (Peer reviewed; Journal article, 2021)
      Background: Physical activity may be a way to increase and maintain fat-free mass (FFM) in later life, similar to the prevention of fractures by increasing peak bone mass. Objectives: A study is presented of the association ...
    • A standard calculation methodology for human doubly labeled water studies 

      Speakman, John R.; Yamada, Yosuke; Sagayama, Hiroyuki; Berman, Elena S.F.; Ainslie, Philip N.; Andersen, Lene Frost; Anderson, Liam J.; Arab, Lenore; Baddou, Issaad; Bedu-Addo, Kweku; Blaak, Ellen E.; Blanc, Stéphane; Bouten, Carlijn V.C.; Bovet, Pascal; Buchowski, Maciej S.; Butte, Nancy F.; Close, Graeme L.; Cooper, Jamie A.; Creasy, Seth A.; Das, Sai Krupa; Cooper, Richard S.; Dugas, Lara R.; Ebbeling, Cara B.; Ekelund, Ulf; Entringer, Sonja; Forrester, Terrence; Fudge, Barry W.; Gurven, Michael; Hambly, Catherine; El Hamdouchi, Asmaa; Hoos, Marije B.; Hu, Sumei; Joonas, Noorjehan; Joosen, Annemiek M.; Katzmarzyk, Peter; Kempen, Kitty P.; Kimura, Misaka; Kraus, William E.; Kushner, Robert F.; Lambert, Estelle V.; Leonard, William R.; Lessan, Nader; Ludwig, David S.; Martin, Corby K.; Medin, Anine Christine; Meijer, Erwin P.; Morehen, James C.; Morton, James P.; Neuhouser, Marian L.; Nicklas, Theresa A.; Ojiambo, Robert M.; Pietiläinen, Kirsi H.; Pitsiladis, Yannis P.; Plange-Rhule, Jacob; Plasqui, Guy; Prentice, Ross L.; Rabinovich, Roberto A.; Racette, Susan B.; Raichlen, David A.; Ravussin, Eric; Reynolds, Rebecca M.; Roberts, Susan B.; Stice, Eric; Urlacher, Samuel S.; Valenti, Giulio; Wilson, George; Wood, Brian M.; Yanovski, Jack; Yoshida, Tsukasa; Zhang, Xueying; Murphy-Alford, Alexia J.; Loechl, Cornelia U.; Melanson, Edward L.; Luke, Amy; Pontzer, Herman; Rood, Jennifer C.; Schoeller, Dale A.; Westerterp, Klaas R.; Wong, William W.; Bonomi, Alberto G.; Camps, Stefan G. J. A.; Goris, Annelies H.; Schuit, Albertine Jantine; Sjödin, Anders M.; van Etten, Ludo M.; van Mil, Edgar A.; Wells, Jonathan C. K. (Peer reviewed; Journal article, 2021)
      The doubly labeled water (DLW) method measures total energy expenditure (TEE) in free-living subjects. Several equations are used to convert isotopic data into TEE. Using the International Atomic Energy Agency (IAEA) DLW ...