Blar i Brage NIH på forfatter "Owens, Daniel J."
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Achieving energy balance with a high‐fat meal does not enhance skeletal muscle adaptation and impairs glycaemic response in a sleep‐low training model
Areta, José; Iraki, Juma; Owens, Daniel J.; Joanisse, Sophie; Philp, Andrew; Morton, James P.; Hallén, Jostein (Peer reviewed; Journal article, 2020)Training with low carbohydrate availability (LCHO) has been shown to acutely enhance endurance training skeletal muscle response, but the concomitant energy deficit (ED) in LCHO interventions has represented a confounding ... -
DNA methylation across the genome in aged human skeletal muscle tissue and muscle‑derived cells: The role of HOX genes and physical activity
Turner, Daniel C.; Gorski, Piotr Patryk; Massar, Mohd Firdaus; Seaborne, Robert A.; Baumert, Phillipp; Brown, Alexander D.; Erskine, Robert M.; Dos-Remedios, Ian; Voisin, Sarah; Eynon, Nir; Borisov, Oleg; Larin, Andrey; Semenova, Ekaterina A.; Popov, Daniil; Drust, Barry; Owens, Daniel J.; Ahmetov, Ildus I.; Sharples, Adam; Kitchen, Mark O.; Sultanov, R. I.; Generozov, Edward V.; Stewart, Claire E. (Peer reviewed; Journal article, 2020)Skeletal muscle tissue demonstrates global hypermethylation with age. However, methylome changes across the time-course of differentiation in aged human muscle derived cells, and larger coverage arrays in aged muscle tissue ... -
Graded reductions in pre-exercise glycogen concentration do not augment exercise-induced nuclear AMPK and PGC-1α protein content in human muscle
Hearris, Mark A.; Owens, Daniel J.; Strauss, Juliette A.; Shepherd, Sam O.; Sharples, Adam; Morton, James P.; Louis, Julien (Peer reviewed; Journal article, 2020)We examined the effects of graded muscle glycogen on the subcellular location and protein content of AMP‐activated protein kinase (AMPK) and peroxisome proliferator‐activated receptor γ coactivator 1α (PGC‐1α) and mRNA ... -
Knockdown of the E3 Ubiquitin ligase UBR5 and its role in skeletal muscle anabolism
Hughes, David C.; Turner, Daniel C.; Baehr, Leslie M.; Seaborne, Robert A.; Viggars, Mark; Jarvis, Jonathan C.; Gorski, Piotr Patryk; Stewart, Claire E.; Owens, Daniel J.; Bodine, Sue C.; Sharples, Adam (Peer reviewed; Journal article, 2020)UBR5 is an E3-ubiquitin-ligase positively associated with anabolism, hypertrophy and recovery from atrophy in skeletal muscle. The precise mechanisms underpinning UBR5's role in the regulation of skeletal muscle mass remains ...