Browsing Brage NIH by Author "Raastad, Truls"
Now showing items 1-20 of 81
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A randomized controlled trial on the effectiveness of strength training on clinical and muscle cellular outcomes in patients with prostate cancer during androgen deprivation therapy: rationale and design
Thorsen, Lene; Nilsen, Tormod S.; Raastad, Truls; Courneya, Kerry S.; Skovlund, Eva; Fosså, Sophie Dorothea (Journal article; Peer reviewed, 2012-03-29)Background Studies indicate that strength training has beneficial effects on clinical health outcomes in prostate cancer patients during androgen deprivation therapy. However, randomized controlled trials are needed to ... -
Active recovery training does not affect the antioxidant response to soccer games in elite female players
Andersson, Helena; Karlsen, Anette; Blomhoff, Rune; Raastad, Truls; Kadi, Fawzi (Journal article; Peer reviewed, 2010-07-08)Changes in plasma endogenous and dietary antioxidants and oxidative stress markers were studied following two 90 min elite female soccer games separated by 72 h of either active or passive recovery. The active recovery ... -
Acute and long-term effects of blood flow restricted training on heat shock proteins and endogenous antioxidant systems
Cumming, Kristoffer Toldnes; Ellefsen, Stian; Rønnestad, Bent; Ugelstad, Ingrid; Raastad, Truls (Journal article; Peer reviewed, 2016)Blood flow restricted exercise (BFRE) with low loads has been demonstrated to induce considerable stress to exercising muscles. Muscle cells have developed a series of defensive systems against exercise-induced stress. ... -
Acute changes in antioxidants and oxidative stress to vigorous arm exercise: An intervention trial in persons with spinal cord injury and healthy controls
Wouda, Matthijs Ferdinand; Slettahjell, Hanne Bjørg; Lundgaard, Eivind; Bastani, Nasser Ezzatkhah; Raastad, Truls; Blomhoff, Rune; Kostovski, Emil (Peer reviewed; Journal article, 2023)Background: Literature remains unclear on possible health benefits and risks assosciated with high intensity exercise for persons with SCI. Elevated oxidative stress levels might influence their ability to exercise at high ... -
Adaptations to strength training differ between endurance-trained and untrained women
Vikmoen, Olav; Raastad, Truls; Ellefsen, Stian; Rønnestad, Bent (Peer reviewed; Journal article, 2020)Purpose: The purpose of this study was to investigate if endurance athletes, sustaining their normal endurance training, experience attenuated adaptations to strength training compared to untrained individuals. Methods: ... -
Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus
Medina-Gomez, Carolina; Kemp, John P.; Dimou, Niki L.; Kreiner, Eskil; Chesi, Alessandra; Zemel, Babette S.; Bønnelykke, Klaus; Boer, Cindy G.; Ahluwalia, Tarunveer S.; Bisgaard, Hans; Evangelou, Evangelos; Heppe, Denise H. M.; Bonewald, Lynda F.; Gorski, Jeffrey P.; Ghanbari, Mohsen; Demissie, Serkalem; Duque, Gustavo; Maurano, Matthew T.; Kiel, Douglas P.; Hsu, Yi-Hsiang; van der Erden, Bram C. J.; Ackert-Bicknell, Cheryl; Reppe, Sjur; Gautvik, Kaare M.; Raastad, Truls; Karasik, David; van de Peppel, Jeroen; Jaddoe, Vincent W. V.; Uitterlinden, Andre G.; Tobias, Jonathan H.; Grant, Struan F. A.; Bagos, Pantelis G.; Evans, David M.; Rivadeneira, Fernando (Journal article; Peer reviewed, 2017)Bone mineral density is known to be a heritable, polygenic trait whereas genetic variants contributing to lean mass variation remain largely unknown. We estimated the shared SNP heritability and performed a bivariate GWAS ... -
Caffeine Increases Strength and Power Performance in Resistance-trained Females During Early Follicular Phase
Norum, Martin; Risvang, Linn; Bjørnsen, Thomas; Dimitriou, Lygeri; Rønning, Per Ola; Bjørgen, Morten; Raastad, Truls (Peer reviewed; Journal article, 2020)The effects of 4 mg·kg−1caffeine ingestion on strength and power were investigated for the first time, in resistance‐trained females during the early follicular phase utilizing a randomized, double‐blind, placebo‐controlled, ... -
Can supplementation with vitamin C and E alter physiological adaptations to strength training?
Paulsen, Gøran; Cumming, Kristoffer Toldnes; Hamarsland, Håvard; Børsheim, Elisabeth; Berntsen, Sveinung; Raastad, Truls (Journal article; Peer reviewed, 2014-07-05)Background: Antioxidant supplementation has recently been demonstrated to be a double-edged sword, because small to moderate doses of exogenous antioxidants are essential or beneficial, while high doses may have adverse ... -
Changes in calpain activity, muscle structure, and function after eccentric exercise
Raastad, Truls; Owe, Simen Gylterud; Paulsen, Gøran; Enns, Deborah; Overgaard, Kristian; Crameri, Regina; Kiil, Steinar; Belcastro, Angelo; Bergersen, Linda Hildegard; Hallén, Jostein (Journal article; Peer reviewed, 2010-01)Purpose: The aim of this study was to investigate changes in muscle function, muscle structure, and calpain activity after high-force eccentric exercise. Methods: Eleven healthy males performed 300 maximal voluntary eccentric ... -
Chronic obstructive pulmonary disease does not impair responses to resistance training
Mølmen, Knut Sindre; Hammarström, Jens Konrad Daniel; Falch, Gunnar Slettaløkken; Grundtvig, Morten; Koll, Lise; Hanestadhaugen, Marita; Khan, Yusuf; Ahmad, Rafi; Malerbakken, Bente; Lien, Roger; Raastad, Truls; Ellefsen, Stian; Rødølen, Tore Jørgen; Rønnestad, Bent R. (Peer reviewed; Journal article, 2021)Background: Subjects with chronic obstructive pulmonary disease (COPD) are prone to accelerated decay of muscle strength and mass with advancing age. This is believed to be driven by disease-inherent systemic pathophysiologies, ... -
Cold water immersion in recovery following a single bout resistance exercise suppresses mechanisms of miRNA nuclear export and maturation
D'Souza, Randall F.; Figueiredo, Vandre C.; Markworth, James F.; Zeng, Nina; Hedges, Christopher P.; Roberts, Llion A.; Raastad, Truls; Coombes, Jeff S.; Peake, Jonathan M.; Mitchell, Cameron J.; Cameron-Smith, David (Peer reviewed; Journal article, 2023)Cold water immersion (CWI) following intense exercise is a common athletic recovery practice. However, CWI impacts muscle adaptations to exercise training, with attenuated muscle hypertrophy and increased angiogenesis. ... -
Consumption of protein-enriched milk has minor effects on inflammation in older adults?A 12-week double-blind randomized controlled trial
Gjevestad, Gyrd Omholt; Ottestad, Inger; Biong, Anne Sofie; Iversen, Per Ole; Retterstøl, Kjetil; Raastad, Truls; Skålhegg, Bjørn Steen; Ulven, Stine Marie; Holven, Kirsten Bjørklund (Journal article; Peer reviewed, 2017)Introduction: Aging is associated with increased levels of circulating inflammatory markers and reduced muscle mass and strength. Objective: We investigated whether intake of protein-enriched milk for 12 weeks would influence ... -
Criteria for the determination of maximal oxygen uptake in patients newly diagnosed with cancer: Baseline data from the randomized controlled trial of physical training and cancer (Phys-Can)
Bjørke, Ann Christin Helgesen; Raastad, Truls; Berntsen, Sveinung (Peer reviewed; Journal article, 2020)Introduction: Maximal oxygen uptake () is a measure of cardiorespiratory fitness often used to monitor changes in fitness during and after treatment in cancer patients. There is, however, limited knowledge in how criteria ... -
Cyclists' improvement of pedaling efficacy and performance after heavy strength training
Hansen, Ernst Albin; Rønnestad, Bent R.; Vegge, Geir; Raastad, Truls (Journal article; Peer reviewed, 2012)The authors tested whether heavy strength training, including hip-flexion exercise, would reduce the extent of the phase in the crank revolution where negative or retarding crank torque occurs. Negative torque normally ... -
Depressed Physical Performance Outlasts Hormonal Disturbances after Military Training
Hamarsland, Håvard; Paulsen, Gøran; Solberg, Paul André; Slaathaug, Ole Gunnar; Raastad, Truls (Journal article; Peer reviewed, 2018). Introduction: The aim of this study was to investigate the effect of an arduous 1-wk military course on measures of physical performance, body composition, and blood biomarkers. Methods: Participants were apprentices in ... -
Dietary Adjustments to Altitude Training in Elite Endurance Athletes; Impact of a Randomized Clinical Trial With Antioxidant-Rich Foods
Koivisto-Mørk, Anu; Paur, Ingvild; Paulsen, Gøran; Garthe, Ina; Raastad, Truls; Bastani, Nasser Ezzatkhah; Blomhoff, Rune; Bøhn, Siv Kjølsrud (Peer reviewed; Journal article, 2020)Background: Altitude training stresses several physiological and metabolic processes and alters the dietary needs of the athletes. International Olympic Committee (IOC)'s Nutrition Expert Group suggests that athletes should ... -
DNA base oxidation in relation to TNM stages and chemotherapy treatment in colorectal cancer patients 2–9 months post-surgery
Nordengen, Anne Lene; Kværner, Ane Sørlie; Krutto, Annika; Alavi, Dena Treider; Henriksen, Hege; Henriksen, Christine; Raastad, Truls; Smeland, Sigbjørn; Kjølsrud Bøhn, Siv; Shaposhnikov, Sergey; Collins, Andrew Richard Sherman; Blomhoff, Rune (Peer reviewed; Journal article, 2024)Accumulation of DNA damage is a critical feature of genomic instability, which is a hallmark of various cancers. The enzyme-modified comet assay is a recognized method to detect specific DNA lesions at the level of individual ... -
Do Paralympic athletes suffer from brittle bones?: Prevalence and risk factors of low bone mineral density in Paralympic athletes
Weijer, Vera C.R.; van Dijk, Jan-Willem; van Dam, Lotte; Risvang, Linn; Bons, Judith; Raastad, Truls; van Loon, Luc J.C.; Jonvik, Kristin Lundanes (Peer reviewed; Journal article, 2024)Background: Bone health may be a concern in Paralympic athletes, given the presence of multiple risk factors predisposing these athletes to low bone mineral density (BMD). Objective: We aimed to assess the prevalence ... -
Does androgen deprivation for prostate cancer affect normal adaptation to resistance exercise?
Nilsen, Tormod Skogstad; Johansen, Sara Hassing; Thorsen, Lene; Fairman, Ciaran M.; Wisløff, Torbjørn; Raastad, Truls (Peer reviewed; Journal article, 2022)Background: Loss of muscle mass and muscle function is a common side effect from androgen deprivation therapy (ADT) for prostate cancer (PCa). Here, we explored effects of heavy-load resistance training (RT) on lean body ... -
Does exercise intensity matter for fatigue during (neo-)adjuvant cancer treatment?: The phys-can randomized clinical trial
Demmelmaier, Ingrid; Brooke, Hannah L.; Henriksson, Anna; Mazzoni, Anne-Sophie; Bjørke, Ann Christin Helgesen; Igelström, Helena; Ax, Anna-Karin; Sjövall, Katarina; Hellbom, Maria; Pingel, Ronnie; Lindman, Henrik; Johansson, Silvia; Velikova, Galina; Raastad, Truls; Buffart, Laurien M.; Åsenlöf, Pernilla; Aaronson, Neil K.; Glimelius, Bengt; Nygren, Peter; Johansson, Birgitta; Börjeson, Sussanne; Berntsen, Sveinung; Nordin, Karin (Peer reviewed; Journal article, 2021)Exercise during cancer treatment improves cancer-related fatigue (CRF), but the importance of exercise intensity for CRF is unclear. We compared the effects of high- vs low-to-moderate-intensity exercise with or without ...