• Evidence against a beneficial effect of irisin in humans 

      Raschke, Silja; Elsen, Manuela; Gassenhuber, Hans; Sommerfeld, Mark; Schwahn, Uwe; Brockmann, Barbara; Jung, Raphael; Wisløff, Ulf; Tjønna, Arnt E.; Raastad, Truls; Hallén, Jostein; Norheim, Frode; Drevon, Christian A.; Romacho, Tania; Eckardt, Kristin; Eckel, Juergen (Journal article; Peer reviewed, 2013-09-11)
      Brown adipose tissue has gained interest as a potential target to treat obesity and metabolic diseases. Irisin is a newly identified hormone secreted from skeletal muscle enhancing browning of white fat cells, which improves ...
    • Identification and validation of novel contraction-regulated myokines released from primary human skeletal muscle cells 

      Raschke, Silja; Eckardt, Kristin; Holven, Kirsten Bjørklund; Jensen, Jørgen; Eckel, Jürgen (Journal article; Peer reviewed, 2013-04-24)
      Proteins secreted by skeletal muscle, so called myokines, have been shown to affect muscle physiology and additionally exert systemic effects on other tissues and organs. Although recent profiling studies have identified ...