Asthma and exercise : climatic effects upon exersice-induced bronchoconstriction and exercise capacity in asthmatic subjects
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The present thesis consists of five studies with the main objective to investigate the effect of different climatic conditions upon exercise capacity and exercise-induced bronchoconstriction (EIB) in subjects with diagnosed EIB (reduction in forced expiratory volume in 1 second (FEV1) ≥ 10% from before to after exercise). In order to assess exercise capacity measured by peak oxygen uptake (V& O2 peak) and peak minute ventilation (V& E peak), two different exercise protocols were evaluated. The usefulness to diagnose EIB in medium altitude by a competitive cross-country skiing field test was compared to assessment of methacholine induced bronchial hyperresponsiveness (BHR) in elite cross-country skiers.Paper I: Stensrud T. and Carlsen K-H. Can one single test protocol for provoking exercise-induced bronchoconstriction also be used for assessing aerobic capacity? Clin Respir Jour 2008. In press.Paper II: Berntsen S., Stensrud T., Ingjer F., Vilberg A., Carlsen K-H. Asthma in medium altitude - exercise-induced bronchoconstriction in hypobaric environment in subjects with asthma. Allergy 2005 Oct; 60(10):1308-11.Paper III: Stensrud T., Berntsen S., Carlsen K-H. Humidity influences exercise capacity in subjects with exercise-induced bronchoconstriction (EIB). Respir Med 2006 Sep; 100(9):1633-41.Paper IV: Stensrud T., Berntsen S., Carlsen K-H. Exercise capacity and exerciseinduced bronchoconstriction in a cold environment. Respir Med 2007 Jul; 101(7):1529-36.Paper V: Stensrud T., Mykland K.V., Gabrielsen K. and Carlsen K-H. Bronchial hyperresponsiveness in skiers: field test versus methacholine provocation? Medicine and Science in Sports and Exercise Med Sci Sports Exerc 2007 Oct; 39(10):1681-6.
Avhandling (doktorgrad) – Norges idrettshøgskole, 2008.