Asthma and exercise : climatic effects upon exersice-induced bronchoconstriction and exercise capacity in asthmatic subjects
Abstract
The present thesis consists of five studies with the main objective to investigate the
effect of different climatic conditions upon exercise capacity and exercise-induced
bronchoconstriction (EIB) in subjects with diagnosed EIB (reduction in forced
expiratory volume in 1 second (FEV1) ≥ 10% from before to after exercise). In order to
assess exercise capacity measured by peak oxygen uptake (V& O2 peak) and peak minute
ventilation (V& E peak), two different exercise protocols were evaluated. The usefulness to
diagnose EIB in medium altitude by a competitive cross-country skiing field test was
compared to assessment of methacholine induced bronchial hyperresponsiveness
(BHR) in elite cross-country skiers. Paper I: Stensrud T. and Carlsen K-H. Can one single test protocol for provoking
exercise-induced bronchoconstriction also be used for assessing aerobic
capacity? Clin Respir Jour 2008. In press. Paper II: Berntsen S., Stensrud T., Ingjer F., Vilberg A., Carlsen K-H. Asthma in
medium altitude - exercise-induced bronchoconstriction in hypobaric
environment in subjects with asthma. Allergy 2005 Oct; 60(10):1308-11. Paper III: Stensrud T., Berntsen S., Carlsen K-H. Humidity influences exercise capacity
in subjects with exercise-induced bronchoconstriction (EIB). Respir Med 2006
Sep; 100(9):1633-41. Paper IV: Stensrud T., Berntsen S., Carlsen K-H. Exercise capacity and exerciseinduced
bronchoconstriction in a cold environment. Respir Med 2007 Jul;
101(7):1529-36. Paper V: Stensrud T., Mykland K.V., Gabrielsen K. and Carlsen K-H. Bronchial
hyperresponsiveness in skiers: field test versus methacholine provocation?
Medicine and Science in Sports and Exercise Med Sci Sports Exerc 2007 Oct;
39(10):1681-6.
Description
Avhandling (doktorgrad) – Norges idrettshøgskole, 2008.