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Aerob kapasitet, lungefunksjon og aktivitetsnivå hos lungekreftpasienter operert ved video-assistert torakoskopi vs torakotomi kirurgi: en prospektiv studie

Rustad, Silje
Master thesis
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URI
http://hdl.handle.net/11250/2390301
Date
2016-05-25
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  • Masteroppgaver / Master's theses [897]
Abstract
Background:

Video-assisted thoracoscopic surgery (VATS) is gaining popularity as a

technique for performing lobectomy in lung cancer. Those patients undergoing VATS

have shown to have lesser pain, shorter hospital stay, lesser blood loss and better

pulmonary function postoperatively than those patients that have undergone

thoracotomy. We have not been able to find any study that has compared these surgery

methods in relation to changes in oxygen uptake and physical activity level in patients

undergoing lung cancer surgery. The aim of the study was therefore to compare

pulmonary function, cardiorespiratory fitness (VO2max) and physical activity level

between VATS and thoracotomy among lung cancer patients.

Subjects and Methods:

37 patients (male =13) with non-small lung cancer underwent either VATS

(n=10) or open thoracotomy. Pulmonary function and VO2max was measured before and

four to six weeks after surgery. In addition, physical activity was measured about six

weeks after surgery with Actigraf for seven consecutive days. Mann-Whitney U test

was used to examine differences in lung function and VO2max between VATS and

thoracotomy. P values of ≤ 0.05 were considered statistically significant.

Results:

Postoperative had VATS patients significantly lower reduction in forced vital

capacity, ventilator capacity and VO2max, respectively 11 % (p=0.04), 16 % (p=0.006)

and 15 % (p=0.008). Moreover, the reduction value in FEV1 was on the significance

limit (14%, p=0.055). There was no difference in change in diffusion capacity between

the groups (27% VATS vs thoracotomy 26 %). VATS patients showed 13 % higher

activity levels measured as steps per day and correspondingly higher intensity expressed

as counts per minute, although not significant (p=0.448). However, there were large

individual differences in activity level in both groups.
Description
Masteroppgaver - Norges idrettshøgskole, 2012

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