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dc.contributor.authorMartin-Rincon, Marcos
dc.contributor.authorGelabert-Rebato, Miriam
dc.contributor.authorGalvan-Alvarez, Victor
dc.contributor.authorGallego-Selles, Angel
dc.contributor.authorMartinez-Canton, Miriam
dc.contributor.authorLopez-Rios, Laura
dc.contributor.authorWiebe, Julia C.
dc.contributor.authorMartin-Rodriguez, Saul
dc.contributor.authorArteaga-Ortiz, Rafael
dc.contributor.authorDorado, Cecilia
dc.contributor.authorPerez-Regalado, Sergio
dc.contributor.authorSantana, Alfredo
dc.contributor.authorMorales-Alamo, David
dc.contributor.authorCalbet, Jose Antonio Lopez
dc.date.accessioned2021-06-04T16:54:10Z
dc.date.available2021-06-04T16:54:10Z
dc.date.created2020-11-05T15:07:55Z
dc.date.issued2020
dc.identifier.citationNutrients. 2020, 12(3), Artikkel 614.en_US
dc.identifier.issn2072-6643
dc.identifier.urihttps://hdl.handle.net/11250/2758003
dc.descriptionThis article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).en_US
dc.description.abstractProlonged or unusual exercise may cause exercise-induced muscle damage (EIMD). To test whether Zynamite®, a mango leaf extract rich in the natural polyphenol mangiferin, administered in combination with quercetin facilitates recovery after EIMD, 24 women and 33 men were randomly assigned to two treatment groups matched by sex and 5 km running performance, and ran a 10 km race followed by 100 drop jumps to elicit EIMD. One hour before the competition, and every 8 h thereafter for 24 h, they ingested placebo (728 mg of maltodextrin) or 140 mg of Zynamite® combined with 140 mg of quercetin (double-blind). Although competition times were similar, polyphenol supplementation attenuated the muscle pain felt after the competition (6.8 ± 1.5 and 5.7 ± 2.2 a.u., p = 0.035) and the loss of jumping performance (9.4 ± 11.5 and 3.9 ± 5.2%, p = 0.036; p = 0.034) and mechanical impulse (p = 0.038) 24 h later. The polyphenols attenuated the increase of serum myoglobin and alanine aminotransferase in men, but not in women (interaction p < 0.05). In conclusion, a single dose of 140 mg Zynamite® combined with 140 mg of quercetin, administered one hour before competition, followed by three additional doses every eight hours, attenuates muscle pain and damage, and accelerates the recovery of muscle performance.en_US
dc.language.isoengen_US
dc.subjectantioxidant supplementationen_US
dc.subjectDOMSen_US
dc.subjecteccentric exerciseen_US
dc.subjectEIMDen_US
dc.subjectergogenic aidsen_US
dc.subjecthuman subjectsen_US
dc.subjectinflammationen_US
dc.subjectmuscle functionen_US
dc.subjectpolyphenolsen_US
dc.subjectsports nutritionen_US
dc.titleSupplementation with a mango leaf extract (Zynamite®) in combination with quercetin attenuates muscle damage and pain and accelerates recovery after strenuous damaging exerciseen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
dc.rights.holder© 2020 by the authorsen_US
dc.source.pagenumber15en_US
dc.source.volume12en_US
dc.source.journalNutrientsen_US
dc.source.issue3en_US
dc.identifier.doi10.3390/nu12030614
dc.identifier.cristin1845348
dc.description.localcodeInstitutt for fysisk prestasjonsevne / Department of Physical Performanceen_US
dc.source.articlenumber614en_US
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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