Effect of high-intensity training on bone health and body composition in lung transplant recipients: A secondary analysis of a randomized controlled trial
dc.contributor.author | Ulvestad, Mariann | |
dc.contributor.author | Godang, Kristin | |
dc.contributor.author | Durheim, Michael T. | |
dc.contributor.author | Kongerud, Johny S. | |
dc.contributor.author | Bollerslev, Jens | |
dc.contributor.author | Edvardsen, Elisabeth | |
dc.contributor.author | Lund, May-Brit | |
dc.date.accessioned | 2021-09-21T11:48:37Z | |
dc.date.available | 2021-09-21T11:48:37Z | |
dc.date.created | 2021-07-15T14:54:34Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Clinical Transplantation. 2021, Artikkel e14375. | en_US |
dc.identifier.issn | 0902-0063 | |
dc.identifier.uri | https://hdl.handle.net/11250/2779876 | |
dc.description | This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. | en_US |
dc.description.abstract | Background: Loss of bone mineral and skeletal muscle mass is common after lung transplantation (LTx), and physical activity (PA) may prevent further deterioration. We aimed to assess the effects of 20-week high-intensity training (HIT) on body composition, bone health, and PA in LTx recipients, 6–60 months after surgery. Methods: In a randomized controlled trial, 51 LTx recipients underwent Dual-energy X-ray absorptiometry (DXA), and PA level and sedentary time were objectively recorded by accelerometers for seven consecutive days. Of these, 39 participants completed the study, including 19 participants in the HIT group and 20 participants in the standard care group. Results: Following the intervention, ANCOVA models revealed a nonsignificant between-group difference for change in lean body mass (LBM) and bone mineral density (BMD) of the lumbar spine of 0.4% (95% CI = −3.2, 1.5) (p = .464) and 1.0% (95% CI=−1.3, 3.4) (p = .373), respectively. Trabecular bone score (TBS) of the lumbar spine (L1-L4), however, increased by 2.2 ± 5.0% in the exercise group and decreased by −1.6 ± 5.9% in the control group, giving a between-group difference of 3.8% (95% CI=0.1, 7.5) (p = .043). There were no between-group differences in PA or sedentary time. Conclusion: High-intensity training after LTx improved TBS significantly, but not PA, LBM or BMD. | en_US |
dc.language.iso | eng | en_US |
dc.subject | clinical trials | en_US |
dc.subject | dual-energy x-ray absorptiometry | en_US |
dc.subject | exercise training | en_US |
dc.subject | osteoporosis | en_US |
dc.subject | sarcopenia | en_US |
dc.title | Effect of high-intensity training on bone health and body composition in lung transplant recipients: A secondary analysis of a randomized controlled trial | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | © 2021 The Authors | en_US |
dc.source.pagenumber | 9 | en_US |
dc.source.journal | Clinical Transplantation | en_US |
dc.identifier.doi | 10.1111/ctr.14375 | |
dc.identifier.cristin | 1921870 | |
dc.description.localcode | Institutt for fysisk prestasjonsevne / Department of Physical Performance | en_US |
dc.source.articlenumber | e14375 | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 |
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