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dc.contributor.authorUlvestad, Mariann
dc.contributor.authorGodang, Kristin
dc.contributor.authorDurheim, Michael T.
dc.contributor.authorKongerud, Johny S.
dc.contributor.authorBollerslev, Jens
dc.contributor.authorEdvardsen, Elisabeth
dc.contributor.authorLund, May-Brit
dc.date.accessioned2021-09-21T11:48:37Z
dc.date.available2021-09-21T11:48:37Z
dc.date.created2021-07-15T14:54:34Z
dc.date.issued2021
dc.identifier.citationClinical Transplantation. 2021, Artikkel e14375.en_US
dc.identifier.issn0902-0063
dc.identifier.urihttps://hdl.handle.net/11250/2779876
dc.descriptionThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.en_US
dc.description.abstractBackground: Loss of bone mineral and skeletal muscle mass is common after lung transplantation (LTx), and physical activity (PA) may prevent further deterioration. We aimed to assess the effects of 20-week high-intensity training (HIT) on body composition, bone health, and PA in LTx recipients, 6–60 months after surgery. Methods: In a randomized controlled trial, 51 LTx recipients underwent Dual-energy X-ray absorptiometry (DXA), and PA level and sedentary time were objectively recorded by accelerometers for seven consecutive days. Of these, 39 participants completed the study, including 19 participants in the HIT group and 20 participants in the standard care group. Results: Following the intervention, ANCOVA models revealed a nonsignificant between-group difference for change in lean body mass (LBM) and bone mineral density (BMD) of the lumbar spine of 0.4% (95% CI = −3.2, 1.5) (p = .464) and 1.0% (95% CI=−1.3, 3.4) (p = .373), respectively. Trabecular bone score (TBS) of the lumbar spine (L1-L4), however, increased by 2.2 ± 5.0% in the exercise group and decreased by −1.6 ± 5.9% in the control group, giving a between-group difference of 3.8% (95% CI=0.1, 7.5) (p = .043). There were no between-group differences in PA or sedentary time. Conclusion: High-intensity training after LTx improved TBS significantly, but not PA, LBM or BMD.en_US
dc.language.isoengen_US
dc.subjectclinical trialsen_US
dc.subjectdual-energy x-ray absorptiometryen_US
dc.subjectexercise trainingen_US
dc.subjectosteoporosisen_US
dc.subjectsarcopeniaen_US
dc.titleEffect of high-intensity training on bone health and body composition in lung transplant recipients: A secondary analysis of a randomized controlled trialen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
dc.rights.holder© 2021 The Authorsen_US
dc.source.pagenumber9en_US
dc.source.journalClinical Transplantationen_US
dc.identifier.doi10.1111/ctr.14375
dc.identifier.cristin1921870
dc.description.localcodeInstitutt for fysisk prestasjonsevne / Department of Physical Performanceen_US
dc.source.articlenumbere14375en_US
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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