dc.contributor.author | Stang, Julie | |
dc.contributor.author | Bråten, Veslemøy | |
dc.contributor.author | Caspersen, Cecilie | |
dc.contributor.author | Thorsen, Einar | |
dc.contributor.author | Stensrud, Trine | |
dc.date.accessioned | 2015-04-20T12:14:02Z | |
dc.date.available | 2015-04-20T12:14:02Z | |
dc.date.issued | 2014-01-22 | |
dc.identifier.citation | Clinical Physiology and Functional Imaging, under utgivelse. doi:10.1111/cpf.12131 | nb_NO |
dc.identifier.uri | http://hdl.handle.net/11250/282098 | |
dc.description | I Brage finner du siste tekst-versjon av artikkelen, og den kan inneholde ubetydelige forskjeller fra forlagets pdf-versjon. Forlagets pdf-versjon finner du på onlinelibrary.wiley.com: http://dx.doi.org/10.1111/cpf.12131 / In Brage you'll find the final text version of the article, and it may contain insignificant differences from the journal's pdf version. The original publication is available at onlinelibrary.wiley.com: http://dx.doi.org/10.1111/cpf.12131 | nb_NO |
dc.description.abstract | Background: Nitric oxide (NO) concentration in exhaled gas is a marker of some inflammatory processes in the lung, and endogenous NO plays a role in the physiological responses to exercise and altitude. The aim of this study was to compare changes in exhaled NO concentration 5–60 mins after high-intensity exercise at 2800 m and at 180 m altitude.
Methods: Twenty trained healthy volunteers (12 men), aged 19–28 years, were included in this open, crossover study. Subjects performed two exercise tests at different altitudes, 2800 m and 180 m, in a randomized order. The fraction of NO in exhaled gas (FENO) was measured 5 mins before and 5–60 mins after 8 mins of running on a treadmill at a heart rate (HR) of 90% of peak HR. Peak HR was assessed during a pretest at 180 m. Ambient temperature was 20·1°C (SD = 1·2) and relative humidity 40·2% (SD = 3·2). FENO measurements were corrected for altitude gas density effects and converted to partial pressure of NO (PENOcorr).
Results: PENOcorr was reduced from 1·47 (1·21, 1·73) millipascal (mPa) at baseline to 1·11 (0·87, 1·34) mPa 5 mins after exercise at 2800 m and from 1·54 (1·24, 1·84) to 1·04 (0·87, 1·22) mPa 5 mins after exercise at 180 m. There was no difference in PENOcorr between exercise at 2800 m and 180 m, and PENOcorr was normalized within 20 mins. | nb_NO |
dc.language.iso | eng | nb_NO |
dc.publisher | Wiley | nb_NO |
dc.subject | airway inflammation | nb_NO |
dc.subject | altitude | nb_NO |
dc.subject | athletes | nb_NO |
dc.subject | endurance sports | nb_NO |
dc.subject | exercise | nb_NO |
dc.subject | ventilation | nb_NO |
dc.title | Exhaled nitric oxide after high-intensity exercise at 2800 m altitude | nb_NO |
dc.type | Journal article | nb_NO |
dc.type | Peer reviewed | nb_NO |
dc.subject.nsi | VDP::Mathematics and natural science: 400::Basic biosciences: 470 | nb_NO |
dc.source.journal | Clinical Physiology and Functional Imaging | nb_NO |
dc.description.localcode | Seksjon for idretssmedisinske fag / Department of Sports Medicine | nb_NO |