Blar i Brage NIH på forfatter "Jensen, Jørgen"
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Rapid radiochemical filter paper assay for determination of hexokinase activity and affinity for glucose-6-phosphate
Hingst, Janne R; Bjerre, Rie D; Wojtaszewski, Jørgen F.P.; Jensen, Jørgen (Peer reviewed; Journal article, 2019)Glucose phosphorylation by hexokinase (HK) is a rate-limiting step in glucose metabolism. Regulation of HK includes feedback inhibition by its product glucose-6-phosphate (G6P) and mitochondria binding. HK affinity for G6P ... -
Regulation of angiopoietin-like protein 4 Production during and after exercise
Norheim, Frode; Hjorth, Marit; Langleite, Torgrim Mikal; Lee, Sindre; Holen, Torgeir; Bindesbøll, Christian; Stadheim, Hans Kristian; Gulseth, Hanne Lovdal; Birkeland, Kåre I.; Kielland, Anders; Jensen, Jørgen; Dalen, Knut Tomas; Drevon, Christian A. (Journal article; Peer reviewed, 2014-08-19)Angiopoietin-like protein 4 (ANGPTL4) may regulate lipoprotein lipase-dependent plasma clearance of triacylglycerol from skeletal muscle during exercise. The aim of this study was to examine the importance of muscle in ... -
The road to the Beijing Winter Olympics and beyond: Opinions and perspectives on physiology and innovation in winter sport
Wang, Jun; Guan, Hongwei; Hostrup, Morten; Rowlands, David S.; González-Alonso, José; Jensen, Jørgen (Peer reviewed; Journal article, 2021)Beijing will host the 2022 Winter Olympics, and China strengthens research on various aspects to allow their athletes to compete successfully in winter sport. Simultaneously, Government-directed initiatives aim to increase ... -
Similar performance after intake of carbohydrate plus whey protein and carbohydrate only in the early phase after non-exhaustive cycling
Sollie, Ove; Clauss, Matthieu; Jeppesen, Per Bendix; Tangen, Daniel S.; Johansen, Egil Ivar; Skålhegg, Bjørn Steen; Ivy, John L.; Jensen, Jørgen (Peer reviewed; Journal article, 2023)Aim: The aim of the present study was to compare performance 5 h after a 90-min endurance training session when either carbohydrate only or carbohydrate with added whey hydrolysate or whey isolate was ingested during the ... -
Sprint interval running and continuous running produce training specific adaptations, despite a similar improvement of aerobic endurance capacity—a randomized trial of healthy adults
Litleskare, Sigbjørn; Enoksen, Eystein; Sandvei, Marit; Støen, Line; Stensrud, Trine; Johansen, Egil Ivar; Jensen, Jørgen (Peer reviewed; Journal article, 2020)The purpose of the present study was to investigate training-specific adaptations to eight weeks of moderate intensity continuous training (CT) and sprint interval training (SIT). Young healthy subjects (n = 25; 9 males ... -
Subsarcolemmal lipid droplet responses to a combined endurance and strength exercise intervention
Li, Yuchuan; Lee, Sindre; Langleite, Torgrim; Norheim, Frode; Pourteymour, Shirin; Jensen, Jørgen; Stadheim, Hans Kristian; Storås, Tryggve H.; Davanger, Svend; Gulseth, Hanne L.; Birkeland, Kåre I.; Drevon, Christian A.; Holen, Torgeir (Journal article; Peer reviewed, 2014)Muscle lipid stores and insulin sensitivity have a recognized association although the mechanism remains unclear. We investigated how a 12‐week supervised combined endurance and strength exercise intervention influenced ... -
The effect of acute and long‐term physical activity on extracellular matrix and serglycin in human skeletal muscle
Hjorth, Marit; Norheim, Frode; Meen, Astri Jeanette; Pourteymour, Shirin; Lee, Sindre; Holen, Torgeir; Jensen, Jørgen; Birkeland, Kåre I.; Martinov, Vladimir Nikolkaev; Langleite, Torgrim Mikal; Eckardt, Kristin; Drevon, Christian A.; Kolset, Svein Olav (Journal article; Peer reviewed, 2015-08-19)Remodeling of extracellular matrix (ECM), including regulation of proteoglycans in skeletal muscle can be important for physiological adaptation to exercise. To investigate the effects of acute and long‐term exercise on ... -
The role of skeletal muscle glycogen breakdown for regulation of insulin sensitivity by exercise
Jensen, Jørgen; Rustad, Per Inge; Kolnes, Anders Jensen; Lai, Yu-Chiang (Journal article; Peer reviewed, 2011-12-30)Glycogen is the storage form of carbohydrates in mammals. In humans the majority of glycogen is stored in skeletal muscles (∼500 g) and the liver (∼100 g). Food is supplied in larger meals, but the blood glucose concentration ... -
Truncation of Pik3r1 causes severe insulin resistance uncoupled from obesity and dyslipidaemia by increased energy expenditure
Kwok, Albert; Zvetkova, Ilona; Virtue, Samuel; Luijten, Ineke; Huang-Doran, Isabel; Tomlinson, Patsy; Bulger, David A.; West, James; Murfitt, Steven; Griffin, Julian; Alam, Rafeah; Hart, Daniel; Knox, Rachel; Voshol, Peter; Vidal-Puig, Antonio; Jensen, Jørgen; O'Rahilly, Stephen; Semple, Robert K. (Peer reviewed; Journal article, 2020)Objective: Insulin signalling via phosphoinositide 3-kinase (PI3K) requires PIK3R1-encoded regulatory subunits. C-terminal PIK3R1 mutations cause SHORT syndrome, as well as lipodystrophy and insulin resistance (IR), ... -
Tyramine reveals failing α2-adrenoceptor control of catecholamine release and total peripheral vascular resistance in hypertensive rats
Berg, Torill; Jensen, Jørgen (Journal article; Peer reviewed, 2013-02-28)α2-Adrenoceptor-activation lowers central sympathetic output, peripheral, vesicular norepinephrine release, epinephrine secretion, and modulates vascular tension. We previously demonstrated that α2-adrenoceptor-mediated ...