Browsing Brage NIH by Author "Gallego-Selles, Angel"
Now showing items 1-8 of 8
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Angiotensin-converting enzyme 2 (SARS-CoV-2 receptor) expression in human skeletal muscle
Perez-Valera, Mario; Martinez-Canton, Miriam; Gallego-Selles, Angel; Gelabert-Rebato, Miriam; Morales-Alamo, David; Santana, Alfredo; Martin-Rodriguez, Saul; Larsen, Steen; Losa-Reyna, Jose; Perez-Suarez, Ismael; Dorado, Cecilia; Curtelin, David; Gonzalez-Henriquez, Juan Jose; Boushel, Robert; Hallén, Jostein; de Pablos-Velasco, Pedro; Freixinet-Gilart, Jorge; Calbet, Jose Antonio Lopez; Galván-Alvarez, Victor; Ponce-Gonzalez, Jesus Gustavo (Peer reviewed; Journal article, 2021)The study aimed to determine the levels of skeletal muscle angiotensin-converting enzyme 2 (ACE2, the SARS-CoV-2 receptor) protein expression in men and women and assess whether ACE2 expression in skeletal muscle is ... -
Antioxidant enzymes and Nrf2/Keap1 in human skeletal muscle: Influence of age, sex, adiposity and aerobic fitness
Galvan-Alvarez, Victor; Gallego-Selles, Angel; Martinez-Canton, Miriam; García-Gonzalez, Eduardo; Gelabert-Rebato, Miriam; Ponce-Gonzalez, Jesus Gustavo; Larsen, Steen; Morales-Alamo, David; Losa-Reyna, Jose; Perez-Suarez, Ismael; Dorado, Cecilia; Perez-Valera, Mario; Holmberg, Hans-Christer; Boushel, Robert; Velasco, Pedro de Pablos; Helge, Jørn Wulff; Martin-Rincon, Marcos; Calbet, José Antonio López (Peer reviewed; Journal article, 2023)Ageing, a sedentary lifestyle, and obesity are associated with increased oxidative stress, while regular exercise is associated with an increased antioxidant capacity in trained skeletal muscles. Whether a higher aerobic ... -
Determinants of the maximal functional reserve during repeated supramaximal exercise by humans: The roles of Nrf2/Keap1, antioxidant proteins, muscle phenotype and oxygenation
Galvan-Alvarez, Victor; Martin-Rincon, Marcos; Gallego-Selles, Angel; Martínez Canton, Miriam; HamedChaman, NaDer; Gelabert-Rebato, Miriam; Perez-Valera, Mario; García-Gonzalez, Eduardo; Santana, Alfredo; Holmberg, Hans-Christer; Boushel, Robert; Hallén, Jostein; Calbet, Jose Antonio Lopez (Peer reviewed; Journal article, 2023)When high-intensity exercise is performed until exhaustion a “functional reserve” (FR) or capacity to produce power at the same level or higher than reached at exhaustion exists at task failure, which could be related to ... -
Fast regulation of the NF-κB signalling pathway in human skeletal muscle revealed by high-intensity exercise and ischaemia at exhaustion: Role of oxygenation and metabolite accumulation
Gallego-Selles, Angel; Galvan-Alvarez, Victor; Martinez-Canton, Miriam; Garcia-Gonzalez, Eduardo; Morales-Alamo, David; Santana, Alfredo; Gonzalez-Henriquez, Juan Jose; Dorado, Cecilia; Calbet, Jose Antonio Lopez; Martin-Rincon, Marcos (Peer reviewed; Journal article, 2022)The NF-κB signalling pathway plays a critical role in inflammation, immunity, cell proliferation, apoptosis, and muscle metabolism. NF-κB is activated by extracellular signals and intracellular changes in Ca2+, Pi, H+, ... -
A mango leaf extract (Zynamite®) combined with Quercetin has exercise-mimetic properties in human skeletal muscle
Martinez-Canton, Miriam; Galvan-Alvarez, Victor; Garcia-Gonzalez, Eduardo; Gallego-Selles, Angel; Gelabert-Rebato, Miriam; Garcia-Perez, Giovanni; Santana, Alfredo; Lopez-Rios, Laura; Vega-Morales, Tanausu; Martin-Rincon, Marcos; Calbet, Jose Antonio Lopez (Peer reviewed; Journal article, 2023)Zynamite PX®, a mango leaf extract combined with quercetin, enhances exercise performance by unknown molecular mechanisms. Twenty-five volunteers were assigned to a control (17 males) or supplementation group (8 males, ... -
Physiological and molecular predictors of cycling sprint performance
Galvan-Alvarez, Victor; Gallego-Selles, Angel; Martinez-Canton, Miriam; Perez-Suarez, Ismael; Garcia-Gonzalez, Eduardo; Martin-Rincon, Marcos; Calbet, Jose Antonio Lopez (Peer reviewed; Journal article, 2024)The study aimed to identify novel muscle phenotypic factors that could determine sprint performance using linear regression models including the lean mass of the lower extremities (LLM), myosin heavy chain composition ... -
Regulation of Nrf2/Keap1 signalling in human skeletal muscle during exercise to exhaustion in normoxia, severe acute hypoxia and post-exercise ischaemia: Influence of metabolite accumulation and oxygenation
Gallego-Selles, Angel; Martin-Rincon, Marcos; Martinez-Canton, Miriam; Perez-Valera, Mario; Martín-Rodríguez, Saúl; Gelabert-Rebato, Miriam; Santana, Alfredo; Morales-Alamo, David; Dorado, Cecilia; Calbet, Jose Antonio Lopez (Peer reviewed; Journal article, 2020)The Nrf2 transcription factor is induced by reactive oxygen and nitrogen species and is necessary for the adaptive response to exercise in mice. It remains unknown whether Nrf2 signalling is activated by exercise in human ... -
Supplementation with a mango leaf extract (Zynamite®) in combination with quercetin attenuates muscle damage and pain and accelerates recovery after strenuous damaging exercise
Martin-Rincon, Marcos; Gelabert-Rebato, Miriam; Galvan-Alvarez, Victor; Gallego-Selles, Angel; Martinez-Canton, Miriam; Lopez-Rios, Laura; Wiebe, Julia C.; Martin-Rodriguez, Saul; Arteaga-Ortiz, Rafael; Dorado, Cecilia; Perez-Regalado, Sergio; Santana, Alfredo; Morales-Alamo, David; Calbet, Jose Antonio Lopez (Peer reviewed; Journal article, 2020)Prolonged or unusual exercise may cause exercise-induced muscle damage (EIMD). To test whether Zynamite®, a mango leaf extract rich in the natural polyphenol mangiferin, administered in combination with quercetin facilitates ...