• Costamere remodeling with muscle loading and unloading in healthy young men 

      Li, Ruowei; Narici, Marco V.; Erskine, Robert M.; Seynnes, Olivier R.; Rittweger, Jörn; Pisot, Rado; Simunic, Bostjan; Flück, Martin (Journal article; Peer reviewed, 2013-09-08)
      Costameres are mechano-sensory sites of focal adhesion in the sarcolemma that provide a structural anchor for myofibrils. Their turnover is regulated by integrin-associated focal adhesion kinase (FAK). We hypothesized that ...
    • Increased Plin2 expression in human skeletal muscle is associated with sarcopenia and muscle weakness 

      Conte, Maria; Vasuri, Francesco; Trisolino, Giovanni; Bellavista, Elena; Santoro, Aurelia; Degiovanni, Alessio; Martucci, Ermanno; D'Errico-Grigoni, Antonia; Caporossi, Daniela; Capri, Miriam; Maier, Andrea B.; Seynnes, Olivier R.; Barberi, Laura; Musaro, Antonio; Narici, Marco V.; Franceschi, Claudio; Salvioli, Stefano (Journal article; Peer reviewed, 2013-08-15)
      Human aging is associated with a progressive loss of muscle mass and strength and a concomitant fat accumulation in form of inter-muscular adipose tissue, causing skeletal muscle function decline and immobilization. Fat ...
    • Local trauma in human patellar tendon leads to widespread changes in the tendon gene expression 

      Heinemeier, Katja M.; Lorentzen, Marc P.; Jensen, Jacob K.; Schjerling, Peter; Seynnes, Olivier R.; Narici, Marco V.; Kjaer, Michael (Journal article; Peer reviewed, 2016-05-01)
      Low cellular activity and slow tissue turnover in human tendon may prolong resolution of tendinopathy. This may be stimulated by moderate localized traumas such as needle penetrations, but whether this results in a widespread ...
    • Physiological and functional evaluation of healthy young and older men and women: design of the European MyoAge study 

      McPhee, Jamie S.; Hogrel, Jean-Yves; Maier, Andrea B.; Seppet, Enn; Seynnes, Olivier R.; Sipilä, Sarianna; Bottinelli, Roberto; Barnouin, Yoann; Bijlsma, Astrid Y.; Gapeyeva, Helena; Maden-Wilkinson, Thomas M.; Meskers, Carel G.; Pääsuke, Mati; Sillanpää, Elina; Sentroth, Lauri; Butler-Browne, Gillian; Narici, Marco V.; Jones, David A. (Journal article; Peer reviewed, 2013-05-31)
      Within the European multi-centre MyoAge project, one workpackage was designed to investigate the contribution of age-related changes to muscle mass, contractile characteristics and neural control in relation to reductions ...