Blar i Brage NIH på tidsskrift "Molecular Metabolism"

Viser treff 1-2 av 2

    • Global mRNA sequencing of human skeletal muscle: Search for novel exercise-regulated myokines 

      Pourteymour, Shirin; Eckardt, Kristin; Holen, Torgeir; Langleite, Torgrim Mikal; Lee, Sindre; Jensen, Jørgen; Birkeland, Kåre I.; Drevon, Christian A.; Hjorth, Marit (Journal article; Peer reviewed, 2017-01)
      Objective: Skeletal muscle is an important secretory organ, producing and releasing numerous myokines, which may be involved in mediating beneficial health effects of physical activity. More than 100 myokines have been ...

    • Truncation of Pik3r1 causes severe insulin resistance uncoupled from obesity and dyslipidaemia by increased energy expenditure 

      Kwok, Albert; Zvetkova, Ilona; Virtue, Samuel; Luijten, Ineke; Huang-Doran, Isabel; Tomlinson, Patsy; Bulger, David A.; West, James; Murfitt, Steven; Griffin, Julian; Alam, Rafeah; Hart, Daniel; Knox, Rachel; Voshol, Peter; Vidal-Puig, Antonio; Jensen, Jørgen; O'Rahilly, Stephen; Semple, Robert K. (Peer reviewed; Journal article, 2020)
      Objective: Insulin signalling via phosphoinositide 3-kinase (PI3K) requires PIK3R1-encoded regulatory subunits. C-terminal PIK3R1 mutations cause SHORT syndrome, as well as lipodystrophy and insulin resistance (IR), ...