Blar i Brage NIH på tidsskrift "Nature Communications"

Viser treff 1-3 av 3

    • Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus 

      Medina-Gomez, Carolina; Kemp, John P.; Dimou, Niki L.; Kreiner, Eskil; Chesi, Alessandra; Zemel, Babette S.; Bønnelykke, Klaus; Boer, Cindy G.; Ahluwalia, Tarunveer S.; Bisgaard, Hans; Evangelou, Evangelos; Heppe, Denise H. M.; Bonewald, Lynda F.; Gorski, Jeffrey P.; Ghanbari, Mohsen; Demissie, Serkalem; Duque, Gustavo; Maurano, Matthew T.; Kiel, Douglas P.; Hsu, Yi-Hsiang; van der Erden, Bram C. J.; Ackert-Bicknell, Cheryl; Reppe, Sjur; Gautvik, Kaare M.; Raastad, Truls; Karasik, David; van de Peppel, Jeroen; Jaddoe, Vincent W. V.; Uitterlinden, Andre G.; Tobias, Jonathan H.; Grant, Struan F. A.; Bagos, Pantelis G.; Evans, David M.; Rivadeneira, Fernando (Journal article; Peer reviewed, 2017)
      Bone mineral density is known to be a heritable, polygenic trait whereas genetic variants contributing to lean mass variation remain largely unknown. We estimated the shared SNP heritability and performed a bivariate GWAS ...

    • Human skeletal muscle plasmalemma alters its structure to change its Ca2+-handling following heavy-load resistance exercise 

      Cully, Tanya R.; Murphy, Robyn M.; Roberts, Llion A.; Raastad, Truls; Fassett, Robert G.; Coombes, Jeff S.; Jayasinghe, Isuru D.; Launikonis, Bradley S. (Journal article; Peer reviewed, 2017)
      High-force eccentric exercise results in sustained increases in cytoplasmic Ca2+ levels ([Ca2+]cyto), which can cause damage to the muscle. Here we report that a heavy-load strength training bout greatly alters the structure ...

    • Total energy expenditure is repeatable in adults but not associated with short-term changes in body composition 

      Rimbach, Rebecca; Yamada, Yosuke; Sagayama, Hiroyuki; Ainslie, Philip N.; Andersen, Lene Frost; Anderson, Liam J.; Arab, Lenore; Baddou, Issaad; Bedu-Addo, Kweku; Blaak, Ellen E.; Blanc, Stephane; Bonomi, Alberto G.; Bouten, Carlijn V. C.; Bovet, Pascal; Buchowski, Maciej S.; Butte, Nancy F.; Camps, Stefan G. J. A.; Close, Graeme L.; Ekelund, Ulf; Pontzer, Herman (Peer reviewed; Journal article, 2022)
      Low total energy expenditure (TEE, MJ/d) has been a hypothesized risk factor for weight gain, but repeatability of TEE, a critical variable in longitudinal studies of energy balance, is understudied. We examine repeated ...