Browsing Brage NIH by Author "Aas, Sigve Nyvik"
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Effects of acute and chronic strength training on skeletal muscle autophagy in frail elderly men and women
Aas, Sigve Nyvik; Tømmerbakke, Daniel; Godager, Sindre; Nordseth, Martin; Armani, Andrea; Sandri, Marco; Benestad, Haakon Breien; Raastad, Truls (Peer reviewed; Journal article, 2020)Aging is associated with alterations in skeletal muscle autophagy, potentially affecting both muscle mass and quality in a negative manner. Strength training with protein supplementation has been reported to improve both ... -
The Effects of Cold Water Immersion and Active Recovery on Molecular Factors That Regulate Growth and Remodeling of Skeletal Muscle After Resistance Exercise
Peake, Jonathan M.; Markworth, James F.; Cumming, Kristoffer Toldnes; Aas, Sigve Nyvik; Roberts, Llion A.; Raastad, Truls; Cameron-Smith, David; Figueiredo, Vandré C. (Peer reviewed; Journal article, 2020)Regular postexercise cooling attenuates muscle hypertrophy, yet its effects on the key molecular factors that regulate muscle growth and remodeling are not well characterized. In the present study, nine men completed two ... -
Effects of strength training on specific strength and muscle protein quality control in frail elderly
Aas, Sigve Nyvik (Doctoral thesis, 2019)With aging, the loss of muscle strength exceeds the loss of muscle mass. Specific strength, defined as strength normalized to the cross-sectional area of a muscle or muscle group, declines accordingly. A reduced voluntary ... -
Effekten av ulike melkeproteinprodukter på hypertrofisignalering etter en styrketreningsøkt
Aas, Sigve Nyvik (Master thesis, 2014)Innledning: Melkeprotein ser ut til å ha en større anabol effekt på muskelvev enn soyaprotein, og det ser også ut til å være forskjeller mellom melkeproteinfraksjonene myse og kasein; med en raskere anabol effekt etter ... -
Muscle protein breakdown is impaired during immobilization compared to during a subsequent retraining period in older men: no effect of anti-inflammatory medication
Dideriksen, K.; Reitelseder, Søren; Agergaard, J.; Boesen, A.P.; Aas, Sigve Nyvik; Raastad, Truls; Holm, Lars (Peer reviewed; Journal article, 2020)Muscle inactivity reduces muscle protein synthesis (MPS), whereas a subsequent period of rehabilitation resistance training (retraining) increases MPS. However, less is known regarding muscle protein breakdown (MPB) during ... -
Musculoskeletal adaptations to strength training in frail elderly: A matter of quantity or quality?
Aas, Sigve Nyvik; Breit, Markus; Karsrud, Stian; Aase, Ole Jølle; Rognlien, Simen Helset; Cumming, Kristoffer Toldnes; Reggiani, Carlo; Seynnes, Olivier R.; Rossi, Andrea; Toniolo, Luana; Raastad, Truls (Peer reviewed; Journal article, 2020)Background The improvement in muscle strength generally exceeds the increase in muscle size following strength training in frail elderly, highlighting the complex aetiology of strength deficit in aging. The aim of this ... -
Native whey induces similar post exercise muscle anabolic responses as regular whey, despite greater leucinemia, in elderly individuals
Hamarsland, Håvard; Aas, Sigve Nyvik; Nordengen, Anne Lene; Holte, Kari; Garthe, Ina; Paulsen, Gøran; Cotter, Matthew; Børsheim, Elisabet; Benestad, Haakon Breien; Raastad, Truls (Journal article; Peer reviewed, 2018)Objective: Elderly muscle seems less sensitive to the anabolic stimulus of a meal. Changes in blood concentrations of leucine are suggested as one important trigger of the anabolic response in muscle. The aim of this study ... -
Native whey protein with high levels of leucine results in similar post-exercise muscular anabolic responses as regular whey protein: A randomized controlled trial
Hamarsland, Håvard; Nordengen, Anne Lene; Aas, Sigve Nyvik; Holte, Kristin Tosterud; Garthe, Ina; Paulsen, Gøran; Cotter, Matthew; Børsheim, Elisabet; Benestad, Haakon Breien; Raastad, Truls (Academic article, 2017-11-21)Protein ingestion produces a strong anabolic stimulus that elevates muscle protein synthesis [34]. The ability of a serving of protein to stimulate muscle protein synthesis (MPS) is dependent on absorption and blood kinetics ... -
Strength training and protein supplementation improve muscle mass, strength, and function in mobility-limited older adults: a randomized controlled trial
Aas, Sigve Nyvik; Seynnes, Olivier R.; Benestad, Haakon Breien; Raastad, Truls (Peer reviewed; Journal article, 2019)Background Adaptation to strength training in very old mobility-limited individuals is not fully characterized. Therefore, the aim of this study was to perform a thorough investigation of the adaptation to a lower body ...