Blar i Brage NIH på forfatter "Hallén, Jostein"
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Achieving energy balance with a high‐fat meal does not enhance skeletal muscle adaptation and impairs glycaemic response in a sleep‐low training model
Areta, José; Iraki, Juma; Owens, Daniel J.; Joanisse, Sophie; Philp, Andrew; Morton, James P.; Hallén, Jostein (Peer reviewed; Journal article, 2020)Training with low carbohydrate availability (LCHO) has been shown to acutely enhance endurance training skeletal muscle response, but the concomitant energy deficit (ED) in LCHO interventions has represented a confounding ... -
Angiotensin-converting enzyme 2 (SARS-CoV-2 receptor) expression in human skeletal muscle
Perez-Valera, Mario; Martinez-Canton, Miriam; Gallego-Selles, Angel; Gelabert-Rebato, Miriam; Morales-Alamo, David; Santana, Alfredo; Martin-Rodriguez, Saul; Larsen, Steen; Losa-Reyna, Jose; Perez-Suarez, Ismael; Dorado, Cecilia; Curtelin, David; Gonzalez-Henriquez, Juan Jose; Boushel, Robert; Hallén, Jostein; de Pablos-Velasco, Pedro; Freixinet-Gilart, Jorge; Calbet, Jose Antonio Lopez; Galván-Alvarez, Victor; Ponce-Gonzalez, Jesus Gustavo (Peer reviewed; Journal article, 2021)The study aimed to determine the levels of skeletal muscle angiotensin-converting enzyme 2 (ACE2, the SARS-CoV-2 receptor) protein expression in men and women and assess whether ACE2 expression in skeletal muscle is ... -
Blood volume expansion does not explain the increase in peak oxygen uptake induced by 10 weeks of endurance training
Skattebo, Øyvind; Bjerring, Anders W.; Auensen, Marius; Sarvari, Sebastian; Cumming, Kristoffer Toldnes; Capelli, Carlo; Hallén, Jostein (Peer reviewed; Journal article, 2020)Purpose: The endurance training (ET)-induced increases in peak oxygen uptake (V˙O2peak) and cardiac output (Q˙peak) during upright cycling are reversed to pre-ET levels after removing the training-induced increase in blood ... -
Changes in calpain activity, muscle structure, and function after eccentric exercise
Raastad, Truls; Owe, Simen Gylterud; Paulsen, Gøran; Enns, Deborah; Overgaard, Kristian; Crameri, Regina; Kiil, Steinar; Belcastro, Angelo; Bergersen, Linda Hildegard; Hallén, Jostein (Journal article; Peer reviewed, 2010-01)Purpose: The aim of this study was to investigate changes in muscle function, muscle structure, and calpain activity after high-force eccentric exercise. Methods: Eleven healthy males performed 300 maximal voluntary eccentric ... -
Contribution of oxygen extraction fraction to maximal oxygen uptake in healthy young men
Skattebo, Øyvind; Calbet, Jose Antonio Lopez; Rud, Bjarne; Capelli, Carlo; Hallén, Jostein (Peer reviewed; Journal article, 2020)We analysed the importance of systemic and peripheral arteriovenous O2 difference (a-vO2 difference and a-vfO2 difference, respectively) and O2 extraction fraction for maximal oxygen uptake (VO2max). Fick law of diffusion ... -
Determinants and reference values for blood volume and total hemoglobin mass in women and men
Oberholzer, Laura; Montero, David; Robach, Paul; Siebenmann, Christoph; Ryrsøe, Camilla Koch; Bonne, Thomas C.; Bejder, Jacob; Karlsen, Trine; Edvardsen, Elisabeth; Hamarsland, Håvard; Cepeda-Lopez, Ana C.; Rittweger, Jörn; Treff, Gunnar; Ahlgrim, Christoph; Almquist, Nicki Winfield; Hallén, Jostein; Andersen, Andreas Breenfeldt; Rønnestad, Bent R.; Lundby, Carsten (Peer reviewed; Journal article, 2024-01-01)Blood volume (BV) is an important clinical parameter and is usually reported per kg of body mass (BM). When fat mass is elevated, this underestimates BV/BM. One aim was to study if differences in BV/BM related to sex, age, ... -
Determinants of the maximal functional reserve during repeated supramaximal exercise by humans: The roles of Nrf2/Keap1, antioxidant proteins, muscle phenotype and oxygenation
Galvan-Alvarez, Victor; Martin-Rincon, Marcos; Gallego-Selles, Angel; Martínez Canton, Miriam; HamedChaman, NaDer; Gelabert-Rebato, Miriam; Perez-Valera, Mario; García-Gonzalez, Eduardo; Santana, Alfredo; Holmberg, Hans-Christer; Boushel, Robert; Hallén, Jostein; Calbet, Jose Antonio Lopez (Peer reviewed; Journal article, 2023)When high-intensity exercise is performed until exhaustion a “functional reserve” (FR) or capacity to produce power at the same level or higher than reached at exhaustion exists at task failure, which could be related to ... -
Distinguishing left ventricular hypertrophy from hypertrophic cardiomyopathy in adolescents: A longitudinal observation study
Forså, Marianne Inngjerdingen; Smedsrud, Marit Kristine; Haugaa, Kristina Ingrid Helena Hermann; Bjerring, Anders W.; Fruh, Andreas; Sarvari, Sebastian I.; Landgraff, Hege Elisabeth Wilson; Hallén, Jostein; Edvardsen, Thor (Peer reviewed; Journal article, 2023)Aims: Echocardiographic characteristics to distinguish physiological left ventricular (LV) hypertrophy from pathology are warranted in early adolescent athletes. This study aimed to explore the phenotype, progression, and ... -
Effects of 150- And 450-mL Acute Blood Losses on Maximal Oxygen Uptake and Exercise Capacity
Skattebo, Øyvind; Johansen, Espen Spro; Capelli, Carlo; Hallén, Jostein (Peer reviewed; Journal article, 2021)Purpose: This study investigated whether maximal oxygen uptake (V˙O2max) and exercise capacity are affected by small acute blood loss (150 mL) and elucidated compensatory mechanisms. Methods: Thirteen male subjects (V˙O2max, ... -
Effects of active versus passive recovery in sprint cross-country skiing.
Losnegard, Thomas; Andersen, Martin; Spencer, Matthew; Hallén, Jostein (Journal article; Peer reviewed, 2015-07-05)Purpose: To investigate the effects of an active and a passive recovery protocol on physiological responses and performance between 2 heats in sprint cross-country skiing. Methods: Ten elite male skiers (22 ± 3 y, 184 ± 4 ... -
Evidence against a beneficial effect of irisin in humans
Raschke, Silja; Elsen, Manuela; Gassenhuber, Hans; Sommerfeld, Mark; Schwahn, Uwe; Brockmann, Barbara; Jung, Raphael; Wisløff, Ulf; Tjønna, Arnt E.; Raastad, Truls; Hallén, Jostein; Norheim, Frode; Drevon, Christian A.; Romacho, Tania; Eckardt, Kristin; Eckel, Juergen (Journal article; Peer reviewed, 2013-09-11)Brown adipose tissue has gained interest as a potential target to treat obesity and metabolic diseases. Irisin is a newly identified hormone secreted from skeletal muscle enhancing browning of white fat cells, which improves ... -
Exercise economy in skiing and running
Losnegard, Thomas; Schäfer, Daniela; Hallén, Jostein (Journal article; Peer reviewed, 2014-01-24)Substantial inter-individual variations in exercise economy exist even in highly trained endurance athletes. The variation is believed to be determined partly by intrinsic factors. Therefore, in the present study, we ... -
From talented child to elite athlete: The development of cardiac morphology and function in a cohort of endurance athletes from age 12 to 18
Bjerring, Anders W.; Landgraff, Hege Wilson; Leirstein, Svein; Haugaa, Kristina; Edvardsen, Thor; Sarvari, Sebastian; Hallén, Jostein (Peer reviewed; Journal article, 2020)Background: Adult athletes undergo cardiac adaptions in what is known as the “athlete’s heart”. Cardiac adaptations in young athletes have not been described in longitudinal studies but have previously been believed to be ... -
Functional reserve and sex differences during exercise to exhaustion revealed by post-exercise ischaemia and repeated supramaximal exercise
Martin-Rincon, Marcos; Gelabert-Rebato, Miriam; Perez-Valera, Mario; Galvan-Alvarez, Victor; Morales-Alamo, David; Dorado, Cecilia; Boushel, Robert; Hallén, Jostein; Calbet, José Antonio López (Peer reviewed; Journal article, 2021)The purpose of this study was to ascertain what mechanisms explain sex differences at task failure and to determine whether males and females have a functional reserve at exhaustion. Exercise performance, cardiorespiratory ... -
Impact of baseline serum ferritin and supplemental iron on altitude-induced hemoglobin mass response in elite athletes
Koivisto-Mørk, Anu; Svendsen, Ida Siobhan; Skattebo, Øyvind; Hallén, Jostein; Paulsen, Gøran (Peer reviewed; Journal article, 2021)The present study explored the impact of pre-altitude serum (s)-ferritin and iron supplementation on changes in hemoglobin mass (ΔHbmass) following altitude training. Measures of Hbmass and s-ferritin from 107 altitude ... -
Individual variations in pre-altitude hemoglobin mass influence hemoglobin mass responses to repeated altitude sojourns
Skattebo, Øyvind; Hallén, Jostein (Peer reviewed; Journal article, 2022)Introduction: Previous studies have shown variable within-subject hemoglobin mass (Hbmass) responses to altitude training. We investigated whether Hbmass responses depend on individual variations in pre-altitude Hbmass ... -
Is the balance between skeletal muscular metabolic capacity and oxygen supply capacity the same in endurance trained and untrained subjects?
Rud, Bjarne; Hallén, Jostein (Peer reviewed; Journal article, 2008-12-02)We attempted to test whether the balance between muscular metabolic capacity and oxygen supply capacity in endurance-trained athletes (ET) differs from that in a control group of normal physically active subjects by using ... -
Kinematic differences between uphill roller skiing and on-snow skiing using the V2 skating technique
Myklebust, Håvard; Losnegard, Thomas Johansen; Hallén, Jostein (Peer reviewed; Journal article, 2022)Purpose: Roller skiing is the primary sport-specific training and testing mode during pre-competition periods for cross-country skiers, biathletes, and Nordic combined athletes. The present study aimed to compare the ... -
Kinematical analysis of the V2 ski skating technique: A longitudinal study
Losnegard, Thomas; Myklebust, Håvard; Ehrhardt, Angela; Hallén, Jostein (Journal article; Peer reviewed, 2017)To characterise timing of movements and evaluate performance effects of technique alterations in V2 ski skating, 13 elite male cross-country skiers (age, 23 ± 2 years; stature, 182 ± 6 cm; body mass, 76 ± 8 kg; V2 V̇O2max, ... -
Longitudinal changes in maximal oxygen uptake in adolescent girls and boys with different training backgrounds
Landgraff, Hege Elisabeth W.; Riiser, Amund; Lihagen, Maren; Skei, Marius; Leirstein, Svein; Hallén, Jostein (Peer reviewed; Journal article, 2021)The purpose of this study was to investigate the effects of high-volume endurance training on the development of maximal oxygen uptake (VO2max) in physically active boys and girls between the ages of 12 and 15 years, using ...