• Aging: a portrait from gene expression profile in blood cells 

      Calabria, Elisa; Mazza, Emilia Maria Cristina; Dyar, Kenneth Allen; Pogliaghi, Silvia; Bruseghini, Paolo; Morandi, Carlo; Salvagno, Gian Luca; Gelati, Matteo; Guidi, Gian Cesare; Bicciato, Silvio; Schiaffino, Stefano; Schena, Frederico; Capelli, Carlo (Journal article; Peer reviewed, 2016-08-19)
      The availability of reliable biomarkers of aging is important not only to monitor the effect of interventions and predict the timing of pathologies associated with aging but also to understand the mechanisms and devise ...
    • Ascs-exosomes recover coupling efficiency and mitochondrial membrane potential in an in vitro model of als 

      Calabria, Elisa; Scambi, Ilaria; Bonafede, Roberta; Schiaffino, Lorenzo; Peroni, Daniele; Potrich, Valentina; Capelli, Carlo; Schena, Federico; Mariotti, Raffaella (Peer reviewed; Journal article, 2019)
      The amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by motoneurons death. Mutations in the superoxide dismutase 1 (SOD1) protein have been identified to be related to the disease. ...
    • Blood volume expansion does not explain the increase in peak oxygen uptake induced by 10 weeks of endurance training 

      Skattebo, Øyvind; Bjerring, Anders W.; Auensen, Marius; Sarvari, Sebastian; Cumming, Kristoffer Toldnes; Capelli, Carlo; Hallén, Jostein (Peer reviewed; Journal article, 2020)
      Purpose: The endurance training (ET)-induced increases in peak oxygen uptake (V˙O2peak) and cardiac output (Q˙peak) during upright cycling are reversed to pre-ET levels after removing the training-induced increase in blood ...
    • Contribution of oxygen extraction fraction to maximal oxygen uptake in healthy young men 

      Skattebo, Øyvind; Calbet, Jose Antonio Lopez; Rud, Bjarne; Capelli, Carlo; Hallén, Jostein (Peer reviewed; Journal article, 2020)
      We analysed the importance of systemic and peripheral arteriovenous O2 difference (a-vO2 difference and a-vfO2 difference, respectively) and O2 extraction fraction for maximal oxygen uptake (VO2max). Fick law of diffusion ...
    • Effect of Endurance and Strength Training on the Slow Component of VO2 Kinetics in Elderly Humans 

      Tam, Enrico; Bruseghini, Paolo; Capelli, Carlo; Oliboni, Eugenio; Pezzato, Andrea; Pogliaghi, Silvia; Mucelli, Roberto Pozzi; Schena, Federico; Calabria, Elisa (Journal article; Peer reviewed, 2018)
      We compared the effects of 8 weeks of high intensity, aerobic interval training (HIT) and isoinertial resistance training (IRT) on: (i) O2 kinetics during heavy (HiEx) intensity exercise and; (ii) work economy during ...
    • Effect of lower body negative pressure on phase I cardiovascular responses at exercise onset 

      Fagoni, Nazzareno; Bruseghini, Paolo; Adami, Alessandra; Capelli, Carlo; Lador, Frederic; Moia, Christian; Tam, Enrico; Bringard, Aurélien; Ferretti, Guido (Peer reviewed; Journal article, 2020)
      We hypothesised that vagal withdrawal and increased venous return interact in determining the rapid cardiac output (CO) response (phase I) at exercise onset. We used lower body negative pressure (LBNP) to increase blood ...
    • Effects of High-Intensity Interval Training and Isoinertial Training on Leg Extensors Muscle Function, Structure, and Intermuscular Adipose Tissue in Older Adults 

      Bruseghini, Paolo; Capelli, Carlo; Calabria, Elisa; Rossi, Andrea; Tam, Enrico (Peer reviewed; Journal article, 2019)
      We compared the effects of aerobic high-intensity training (HIT) and isoinertial resistance training (IRT) on the strength, mass, architecture, intermuscular adipose tissue (IMAT) quality, and neuromuscular activation of ...
    • Exercise performance increase in smokeless tobacco‐user athletes after overnight nicotine abstinence 

      Zandonai, Thomas; Tam, Enrico; Bruseghini, Paolo; Capelli, Carlo; Baraldo, Massimo; Chiamulera, Cristiano (Journal article; Peer reviewed, 2019)
      The use of nicotine administered through smokeless tobacco (snus) has increased among athletes. The purpose of this study was to investigate the ergogenic effects of snus on aerobic performance during exercise until ...
    • Maximal aerobic power and anaerobic capacity in cycling across the age spectrum in male master athletes 

      Capelli, Carlo; Rittveger, J.; Bruseghini, Paolo; Calabria, E.; Tam, Enrico (Journal article; Peer reviewed, 2016-05)
      Purpose: We analyzed the best performance times of master cycling athletes in the 200–3000 m track competitions to estimate the decay of maximal aerobic power (MAP) and anaerobic capacity (AnS) with aging. Methods: In ...
    • Metabolic and kinematic responses while walking and running on a motorised and a curved non-motorised treadmill 

      Bruseghini, Paolo; Tam, Enrico; Monte, Andrea; Capelli, Carlo; Zamparo, Paola (Journal article; Peer reviewed, 2018)
      The purpose of this study was to assess metabolic and kinematic parameters (contact and flight time, step length and frequency) while walking at the preferred speed (1.44 ± 0.22 m · s−1) and while performing an incremental ...
    • Metabolic and performance effects of Yerba Mate on well-trained cyclists 

      Areta, José; Austarheim, Ingvild; Wangensteen, Helle; Capelli, Carlo (Journal article; Peer reviewed, 2017)
      Introduction: Yerba Mate (YM) is a South-American plant, rich in polyphenols, saponins and xanthines, of growing scientific interest due to its metabolic effects. YM has been shown to increase fat utilization during exercise ...
    • The effects of oral smokeless tobacco administration on endurance performance 

      Zandonai, Thomas; Tam, Enrico; Bruseghini, Paolo; Pizzolato, Fabio; Franceschi, Loretta; Baraldo, Massimo; Capelli, Carlo; Cesari, Paola; Chiamulera, Cristiano (Peer reviewed; Journal article, 2017)
      Background: Smokeless tobacco is widely used by athletes to enhance performance. Nicotine is a central nervous system stimulant and acts on cardiocirculatory and metabolic systems, involving tissue blood flow and circulatory ...