• Branched-chain amino acid metabolism, insulin sensitivity and liver fat response to exercise training in sedentary dysglycaemic and normoglycaemic men 

      Lee, Sindre; Gulseth, Hanne Løvdal; Langleite, Torgrim Mikal; Norheim, Frode; Olsen, Thomas; Refsum, Helga; Jensen, Jørgen; Birkeland, Kåre I.; Drevon, Christian A (Peer reviewed; Journal article, 2020)
      Aims/hypothesis: Obesity and insulin resistance may be associated with elevated plasma concentration of branched-chain amino acids (BCAAs) and impaired BCAA metabolism. However, it is unknown whether the insulin-sensitising ...
    • Dual specificity phosphatase 5 and 6 are oppositely regulated in human skeletal muscle by acute exercise 

      Pourteymour, Shirin; Hjorth, Marit; Lee-Ødegård, Sindre; Holen, Torgeir; Langleite, Torgrim Mikal; Jensen, Jørgen; Birkeland, Kåre I.; Drevon, Christian A; Eckardt, Kristin (Journal article; Peer reviewed, 2017)
      Physical activity promotes specific adaptations in most tissues including skeletal muscle. Acute exercise activates numerous signaling cascades including pathways involving mitogen‐activated protein kinases (MAPKs) such ...
    • Exercise in vivo marks human myotubes in vitro: Training-induced increase in lipid metabolism 

      Lund, Jenny; Rustan, Arild; Løvsletten, Nils Gunnar; Mudry, Jonathan M.; Langleite, Torgrim Mikal; Feng, Yuan Zeng; Stensrud, Camilla; Brubak, Mari G; Drevon, Christian A; Birkeland, Kåre I.; Kolnes, Kristoffer Jensen; Johansen, Egil Ivar; Tangen, Daniel S.; Stadheim, Hans Kristian; Gulseth, Hanne Løvdal; Krook, Anna; Kase, Eili Tranheim; Jensen, Jørgen; Thoresen, G. Hege (Peer reviewed; Journal article, 2017)
      Background and aims: Physical activity has preventive as well as therapeutic benefits for overweight subjects. In this study we aimed to examine effects of in vivo exercise on in vitro metabolic adaptations by studying ...
    • Global mRNA sequencing of human skeletal muscle: Search for novel exercise-regulated myokines 

      Pourteymour, Shirin; Eckardt, Kristin; Holen, Torgeir; Langleite, Torgrim Mikal; Lee, Sindre; Jensen, Jørgen; Birkeland, Kåre I.; Drevon, Christian A.; Hjorth, Marit (Journal article; Peer reviewed, 2017-01)
      Objective: Skeletal muscle is an important secretory organ, producing and releasing numerous myokines, which may be involved in mediating beneficial health effects of physical activity. More than 100 myokines have been ...
    • Molecular nutrition research: the modern way of performing nutritional science 

      Norheim, Frode; Gjelstad, Ingrid Merethe Fange; Hjorth, Marit; Vinknes, Kathrine; Langleite, Torgrim Mikal; Jensen, Jørgen; Dalen, Knut Tomas; Karlsen, Anette; Kielland, Anders; Rustan, Arild; Drevon, Christian A. (Journal article; Peer reviewed, 2012-12-03)
      In spite of amazing progress in food supply and nutritional science, and a striking increase in life expectancy of approximately 2.5 months per year in many countries during the previous 150 years, modern nutritional ...
    • Regulation of angiopoietin-like protein 4 Production during and after exercise 

      Norheim, Frode; Hjorth, Marit; Langleite, Torgrim Mikal; Lee, Sindre; Holen, Torgeir; Bindesbøll, Christian; Stadheim, Hans Kristian; Gulseth, Hanne Lovdal; Birkeland, Kåre I.; Kielland, Anders; Jensen, Jørgen; Dalen, Knut Tomas; Drevon, Christian A. (Journal article; Peer reviewed, 2014-08-19)
      Angiopoietin-like protein 4 (ANGPTL4) may regulate lipoprotein lipase-dependent plasma clearance of triacylglycerol from skeletal muscle during exercise. The aim of this study was to examine the importance of muscle in ...
    • The effect of acute and long‐term physical activity on extracellular matrix and serglycin in human skeletal muscle 

      Hjorth, Marit; Norheim, Frode; Meen, Astri Jeanette; Pourteymour, Shirin; Lee, Sindre; Holen, Torgeir; Jensen, Jørgen; Birkeland, Kåre I.; Martinov, Vladimir Nikolkaev; Langleite, Torgrim Mikal; Eckardt, Kristin; Drevon, Christian A.; Kolset, Svein Olav (Journal article; Peer reviewed, 2015-08-19)
      Remodeling of extracellular matrix (ECM), including regulation of proteoglycans in skeletal muscle can be important for physiological adaptation to exercise. To investigate the effects of acute and long‐term exercise on ...