• Alpine skiing with total knee arthroplasty (ASWAP): effect on tendon properties 

      Kösters, Alexander; Rieder, Florian; Wiesinger, H. P.; Dorn, U.; Hofstaedter, T.; Fink, Christian; Müller, E.; Seynnes, Olivier R. (Journal article; Peer reviewed, 2015-06-10)
      The aim of this study was to investigate the effect of alpine skiing on patellar tendon properties in patients with total knee arthroplasty (TKA). Thirty-one adults (70.4 ± 4.7 years) with unilateral TKA were recruited ...
    • Alpine skiing with total knee arthroplasty (ASWAP): muscular adaptations 

      Rieder, Florian; Kösters, Alexander; Wiesinger, H. P.; Dorn, U.; Hofstaedter, T.; Fink, Christian; Müller, E.; Seynnes, Olivier R. (Journal article; Peer reviewed, 2015-06-17)
      This study investigated the effectiveness of recreational skiing as an intervention to improve quadriceps muscle architecture, strength, and antagonistic co-activation in patients with unilateral total knee arthroplasty ...
    • Are sport-specific profiles of tendon stiffness and cross-sectional area determined by structural or functional integrity? 

      Wiesinger, Hans-Peter; Rieder, Florian; Kösters, Alexander; Müller, Erich; Seynnes, Olivier R. (Journal article; Peer reviewed, 2016-06-30)
      The present study aimed to determine whether distinct sets of tendon properties are seen in athletes engaged in sports with contrasting requirements for tendon function and structural integrity. Patellar and Achilles tendon ...
    • Costamere remodeling with muscle loading and unloading in healthy young men 

      Li, Ruowei; Narici, Marco V.; Erskine, Robert M.; Seynnes, Olivier R.; Rittweger, Jörn; Pisot, Rado; Simunic, Bostjan; Flück, Martin (Journal article; Peer reviewed, 2013-09-08)
      Costameres are mechano-sensory sites of focal adhesion in the sarcolemma that provide a structural anchor for myofibrils. Their turnover is regulated by integrin-associated focal adhesion kinase (FAK). We hypothesized that ...
    • Eccentric cycling does not improve cycling performance in amateur cyclists 

      Paulsen, Gøran; Eidsheim, Hedda; Helland, Christian; Seynnes, Olivier R.; Solberg, Paul Andre; Rønnestad, Bent (Peer reviewed; Journal article, 2019)
      Eccentric cycling training induces muscle hypertrophy and increases joint power output in non-athletes. Moreover, eccentric cycling can be considered a movement-specific type of strength training for cyclists, but it is ...
    • Effect of traditional and resisted sprint training in highly-trained, female team handball players 

      Luteberget, Live S.; Raastad, Truls; Seynnes, Olivier R.; Spencer, Matt (Journal article; Peer reviewed, 2014)
      Fast acceleration is an important performance factor in handball. In addition to traditional sprint training (TST), resisted sprint training (RST) is a method often used to improve acceleration. However, studies on RST ...
    • Effects of heavy strength training on running performance and determinants of running performance in female endurance athletes 

      Vikmoen, Olav; Raastad, Truls; Seynnes, Olivier R.; Bergstrøm, Kristoffer; Ellefsen, Stian; Rønnestad, Bent R. (Journal article; Peer reviewed, 2016-03-08)
      Purpose: The purpose of the current study was to investigate the effects of adding strength training to normal endurance training on running performance and running economy in well-trained female athletes. We hypothesized ...
    • Effects of increased loading on in vivo tendon properties: a systematic review 

      Wiesinger, Hans-Peter; Kösters, Alexander; Müller, Erich; Seynnes, Olivier R. (Journal article; Peer reviewed, 2015-09)
      Introduction: In vivo measurements have been used in the past two decades to investigate the effects of increased loading on tendon properties, yet the current understanding of tendon macroscopic changes to training is ...
    • Effects of tracking landmarks and tibial point of resistive force application on the assessment of patellar tendon mechanical properties in vivo 

      Mersmann, Falk; Seynnes, Olivier R.; Legerlotz, Kirsten; Arampatzis, Adamantios (Journal article; Peer reviewed, 2018)
      The different methods used to assess patellar tendon elongation in vivo may partly explain the large variation of mechanical properties reported in the literature. The present study investigated the effects of tracking ...
    • Human skeletal muscle fibre contractile properties and proteomic profile: adaptations to 3 weeks of unilateral lower limb suspension and active recovery 

      Brocca, Lorenza; Longa, Emanuela; Cannavino, Jessica; Seynnes, Olivier R.; de Vito, Giuseppe; McPhee, Jamie; Narici, Marco; Pellegrino, Maria Antonietta; Bottinelli, Roberto (Journal article; Peer reviewed, 2015-12-15)
      Following disuse, muscle fibre function goes through adaptations such as a loss of specific force (PO/CSA) and an increase in unloaded shortening velocity, which could be a result of both quantitative changes (i.e. atrophy) ...
    • Immediate effects of whole body vibration on patellar tendon properties and knee extension torque 

      Rieder, Florian; Wiesinger, Hans-Peter; Kösters, Alexander; Müller, Erich; Seynnes, Olivier R. (Journal article; Peer reviewed, 2016-03)
      Purpose: Reports about the immediate effects of whole body vibration (WBV) exposure upon torque production capacity are inconsistent. However, the changes in the torque–angle relationship observed by some authors after WBV ...
    • Increased Plin2 expression in human skeletal muscle is associated with sarcopenia and muscle weakness 

      Conte, Maria; Vasuri, Francesco; Trisolino, Giovanni; Bellavista, Elena; Santoro, Aurelia; Degiovanni, Alessio; Martucci, Ermanno; D'Errico-Grigoni, Antonia; Caporossi, Daniela; Capri, Miriam; Maier, Andrea B.; Seynnes, Olivier R.; Barberi, Laura; Musaro, Antonio; Narici, Marco V.; Franceschi, Claudio; Salvioli, Stefano (Journal article; Peer reviewed, 2013-08-15)
      Human aging is associated with a progressive loss of muscle mass and strength and a concomitant fat accumulation in form of inter-muscular adipose tissue, causing skeletal muscle function decline and immobilization. Fat ...
    • Influence of loading rate on patellar tendon mechanical properties in vivo 

      Kösters, Alexander; Wiesinger, H. P.; Bojsen-Møller, Jens; Müller, E.; Seynnes, Olivier R. (Journal article; Peer reviewed, 2014-03)
      Background: Rate-dependent properties of tendons have consistently been observed in vitro but in vivo studies comparing the effects of loading duration on this feature remain conflicting. The main purpose of the present ...
    • Isokinetic resistance training combined with eccentric overload improves athletic performance and induces muscle hypertrophy in young ice hockey players 

      Horwath, Oscar; Paulsen, Gøran; Esping, Tobias; Seynnes, Olivier R.; Olsson, Monica Charlotte (Peer reviewed; Journal article, 2019)
      Objectives: To determine the combined effects of slow isokinetic resistance training and eccentric overload and compare it to traditional resistance training on strength, power, body composition and muscle hypertrophy in ...
    • Local trauma in human patellar tendon leads to widespread changes in the tendon gene expression 

      Heinemeier, Katja M.; Lorentzen, Marc P.; Jensen, Jacob K.; Schjerling, Peter; Seynnes, Olivier R.; Narici, Marco V.; Kjaer, Michael (Journal article; Peer reviewed, 2016-05-01)
      Low cellular activity and slow tissue turnover in human tendon may prolong resolution of tendinopathy. This may be stimulated by moderate localized traumas such as needle penetrations, but whether this results in a widespread ...
    • Mechanical properties of the patellar tendon in elite volleyball players with and without patellar tendinopathy 

      Helland, Christian; Bojsen-Møller, Jens; Raastad, Truls; Seynnes, Olivier R.; Moltubakk, Marie M.; Jakobsen, Vidar; Bahr, Roald (Journal article; Peer reviewed, 2013)
      Background: Although differences in mechanical properties between symptomatic and healthy tendons have been observed for the Achilles tendon, the impact of tendinopathy on patellar tendon mechanics is not fully documented. ...
    • Physiological and functional evaluation of healthy young and older men and women: design of the European MyoAge study 

      McPhee, Jamie S.; Hogrel, Jean-Yves; Maier, Andrea B.; Seppet, Enn; Seynnes, Olivier R.; Sipilä, Sarianna; Bottinelli, Roberto; Barnouin, Yoann; Bijlsma, Astrid Y.; Gapeyeva, Helena; Maden-Wilkinson, Thomas M.; Meskers, Carel G.; Pääsuke, Mati; Sillanpää, Elina; Sentroth, Lauri; Butler-Browne, Gillian; Narici, Marco V.; Jones, David A. (Journal article; Peer reviewed, 2013-05-31)
      Within the European multi-centre MyoAge project, one workpackage was designed to investigate the contribution of age-related changes to muscle mass, contractile characteristics and neural control in relation to reductions ...
    • Sarcolab pilot study into skeletal muscle’s adaptation to long-term spaceflight 

      Rittweger, Jörn; Albracht, Kirsten; Flück, Martin; Ruoss, Severin; Brocca, Lorenza; Longa, Emanuela; Moriggi, Manuela; Seynnes, Olivier R.; di Giulio, Irene; Tenori, Leonardo; Vignoli, Alessia; Capri, Miriam; Gelfi, Cecilia; Luchinat, Claudio; Franceschi, Claudio; Bottinelli, Roberto; Cerretelli, Paolo; Narici, Marco (Journal article; Peer reviewed, 2018)
      Spaceflight causes muscle wasting. The Sarcolab pilot study investigated two astronauts with regards to plantar flexor muscle size, architecture, and function, and to the underlying molecular adaptations in order to further ...
    • Single muscle fibre contractile properties differ between body-builders, power athletes and control subjects 

      Meijer, J.P; Jaspers, R.T.; Rittweger, Jörn; Seynnes, Olivier R.; Kamandulis, Sigitas; Brazaitis, M.; Skurvydas, A.; Pisot, Rado; Šimunič, Boštjan; Narici, Maco V.; Degens, Hans (Journal article; Peer reviewed, 2015-11-17)
      What is the central question of this study? Do the contractile properties of single muscle fibres differ between body-builders, power athletes and control subjects? •What is the main finding and its importance? Peak ...
    • Skeletal muscle adaptations to physical inactivity and subsequent retraining in young men 

      Campbell, Emma-Louise; Seynnes, Olivier R.; Bottinelli, R.; McPhee, Jamie S.; Atherton, P. J.; Jones, D. A.; Butler-Browne, Gillian; Narici, Maco V. (Journal article; Peer reviewed, 2013-05-12)
      Skeletal muscle structure and function are markedly affected by chronic disuse. With unloading, muscle mass is lost at rate of about 0.4 %/day but little is known about the recovery of muscle mass and strength following ...