dc.contributor.author | Edvardsen, Elisabeth | |
dc.contributor.author | Akerø, Aina | |
dc.contributor.author | Skjønsberg, Ole Henning | |
dc.contributor.author | Skrede, Bjørn | |
dc.date.accessioned | 2017-08-28T09:19:48Z | |
dc.date.available | 2017-08-28T09:19:48Z | |
dc.date.issued | 2017-02-06 | |
dc.identifier.citation | BMC Research Notes. 2017, 10, doi: 10.1186/s13104-017-2386-2 | nb_NO |
dc.identifier.uri | http://hdl.handle.net/11250/2452009 | |
dc.description.abstract | Background: Air travel may imply a health hazard for patients with cystic fibrosis (CF) due to hypobaric environment in the aircraft cabin. The objective was to identify pre-flight variables, which might predict severe hypoxaemia in adult CF patients during air travel. Methods: Thirty adult CF-patients underwent pre-flight evaluation with spirometry, arterial oxygen tension (PaO2), pulse oximetry (SpO2) and cardiopulmonary exercise testing (CPET) at sea level (SL). The results were related to the PaO2 obtained during a hypoxia-altitude simulation test (HAST) in which a cabin altitude of 2438 m (8000 ft) was simulated by breathing 15.1% oxygen. Results: Four patients fulfilled the criteria for supplemental oxygen during air travel (PaO2 HAST < 6.6 kPa). While walking slowly during HAST, another eleven patients dropped below PaO2 HAST 6.6 kPa. Variables obtained during CPET (PaO2 CPET, SpO2 CPET, minute ventilation/carbon dioxide output, maximal oxygen uptake) showed the strongest correlation to PaO2 HAST. Conclusions: Exercise testing might be of value for predicting in-flight hypoxaemia and thus the need for supplemental oxygen during air travel in CF patients. | nb_NO |
dc.language.iso | eng | nb_NO |
dc.publisher | BioMed Central | nb_NO |
dc.subject | blood gas response | nb_NO |
dc.subject | cardiopulmonary exercise testing | nb_NO |
dc.subject | gas exchange | nb_NO |
dc.subject | hypoxia altitude simulation test | nb_NO |
dc.subject | pulmonary function | nb_NO |
dc.title | Pre-flight evaluation of adult patients with cystic fibrosis: a cross-sectional study | nb_NO |
dc.type | Journal article | nb_NO |
dc.type | Peer reviewed | nb_NO |
dc.source.journal | BMC Research Notes | nb_NO |
dc.identifier.doi | 10.1186/s13104-017-2386-2 | |
dc.description.localcode | Seksjon for idrettsmedisinske fag / Department of Sports Medicine | nb_NO |