Cross-sectional associations of objectively measured physical activity with brain-derived neurotrophic factor in adolescents
Journal article, Peer reviewed
Accepted version
Permanent lenke
http://hdl.handle.net/11250/2496514Utgivelsesdato
2017Metadata
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Sammendrag
Objective: The purpose of this study was to examine the associations between objectively measured physical activity and serum brain-derived neurotrophic factor (BDNF) in adolescents. Methods: Cross-sectional analyses were performed using data from 415 adolescents who participated in the 2015 follow-up of the Childhood Health Activity and Motor Performance School Study Denmark (the CHAMPS-study DK). Physical activity was objectively measured by accelerometry monitors. Serum BDNF levels were analyzed using the Enzyme-linked immunosorbent assay (ELISA). Anthropometrics and pubertal status were measured using standardized procedures. Results: With adjustment for age, pubertal status and body mass index, mean physical activity (counts per minute) was negatively associated with serum BDNF in boys (P = 0.013). Similarly, moderate-to-vigorous physical activity (MVPA) was negatively associated with serum BDNF in boys (P = 0.035). In girls, mean physical activity and MVPA were not associated with serum BDNF. Without adjustment for wear time, sedentary time was not associated with serum BDNF in either sex. Conclusion: These findings indicate that higher physical activity is associated with lower serum BDNF in boys, but not in girls.
Beskrivelse
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