dc.contributor.author | Banitalebi, Hasan | |
dc.contributor.author | Owesen, Christian | |
dc.contributor.author | Årøen, Asbjørn | |
dc.contributor.author | Tran, Hang Thi | |
dc.contributor.author | Myklebust, Tor Åge | |
dc.contributor.author | Randsborg, Per-Henrik | |
dc.date.accessioned | 2022-03-22T00:59:19Z | |
dc.date.available | 2022-03-22T00:59:19Z | |
dc.date.created | 2021-05-28T11:03:49Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Journal of Experimental Orthopaedics. 2021, 8(2021), Artikkel 34. | en_US |
dc.identifier.issn | 2197-1153 | |
dc.identifier.uri | https://hdl.handle.net/11250/2986661 | |
dc.description | This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. | en_US |
dc.description.abstract | Purpose: To evaluate the effect of imaging plane and experience of observers on the reliability of T2 mapping of native and repair cartilage tissue of the knee.
Methods: Fifteen consecutive patients from two randomised controlled trials (RCTs) were included in this cross-sectional study. Patients with an isolated knee cartilage lesion were randomised to receive either debridement or microfracture (RCT 1) or debridement or autologous chondrocyte implantation (RCT 2). T2 mapping was performed in coronal and sagittal planes two years postoperatively. A musculoskeletal radiologist, a resident of radiology and two orthopaedic surgeons measured the T2 values independently. Intraclass Correlation Coefficient (ICC) with 95% Confidence Intervals was used to calculate the inter- and intraobserver agreement.
Results: Mean age for the patients was 36.8 ± 11 years, 8 (53%) were men. The overall interobserver agreement varied from poor to good with ICCs in the range of 0.27– 0.76 for native cartilage and 0.00 – 0.90 for repair tissue. The lowest agreement was achieved for evaluations of repair cartilage tissue. The estimated ICCs suggested higher inter- and intraobserver agreement for radiologists. On medial femoral condyles, T2 values were higher for native cartilage on coronal images (p < 0.001) and for repair tissue on sagittal images (p < 0.001).
Conclusions: The reliability of T2 mapping of articular cartilage is influenced by the imaging plane and the experience of the observers. This influence may be more profound for repair cartilage tissue. This is important to consider when using T2 mapping to measure outcomes after cartilage repair surgery.
Trial registration: ClinicalTrials.gov, NCT02637505 and NCT02636881, registered December 2015.
Level of evidence: II, based on prospective data from two RCTs. | en_US |
dc.language.iso | eng | en_US |
dc.relation.uri | https://jeo-esska.springeropen.com/articles/10.1186/s40634-021-00350-1 | |
dc.subject | articular cartilage | en_US |
dc.subject | autologous chondrocyte implantation | en_US |
dc.subject | cartilage repair | en_US |
dc.subject | MRI | en_US |
dc.subject | reliability | en_US |
dc.subject | T2 mapping | en_US |
dc.title | Is T2 mapping reliable in evaluation of native and repair cartilage tissue of the knee? | en_US |
dc.type | Peer reviewed | en_US |
dc.type | Journal article | en_US |
dc.description.version | publishedVersion | en_US |
dc.rights.holder | © The Author(s) 2021 | en_US |
dc.source.pagenumber | 10 | en_US |
dc.source.volume | 8 | en_US |
dc.source.journal | Journal of Experimental Orthopaedics | en_US |
dc.identifier.doi | 10.1186/s40634-021-00350-1 | |
dc.identifier.cristin | 1912476 | |
dc.relation.project | Norges forskningsråd: 148583 | en_US |
dc.description.localcode | Institutt for idrettsmedisinske fag / Department of Sports Medicine | en_US |
dc.source.articlenumber | 34 | en_US |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 1 | |