Expired nitric oxide after high intensive exercise at altitude
Abstract
Nitric oxide has, as an exhaled biomarker, become an accepted tool in the management
of inflammatory airway diseases, with its non-invasive, quick and easy measurement
procedures. However, its use is still discussed and NO have currently only been
assigned a complementary value. Other studies have reported reduced partial pressure of
expired [NO] (PENO) at altitude (Hemmingsson and Linnarsson, 2009) and acute
hypoxia is shown to down-regulate NO synthesis (Brown et al., 2006). Exercise alter
values of expired NO concentration (FENO) (Shin et al., 2003). A large individual
variance of FENO has also been reported in the literature (Olivieri et al., 2006). Different
methods (i. e. flow rate) and measurement equipment may account for some of the
variety of available research results and materials today. The purpose of this study was
to examine changes in and the course of expired [NO] (FENO and PENO) after high
intensive exercise, during exposure to reduced barometric pressure.
Description
Masteroppgave – Norges idrettshøgskole, 2010.